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日本的高血压与预期寿命:NIPPON DATA80。

Hypertension and life expectancy among Japanese: NIPPON DATA80.

机构信息

Department of Medicine, University of Calgary, Alberta, Canada.

出版信息

Hypertens Res. 2012 Sep;35(9):954-8. doi: 10.1038/hr.2012.86. Epub 2012 Jul 5.

DOI:10.1038/hr.2012.86
PMID:22763482
Abstract

Life expectancy (LE) is a measure that describes the health status of a population. The few published studies that have examined the impact of hypertension on LE were predominantly performed in Western populations. The effect of hypertension on LE has not been reported in an Asian population. Thus, we examined the impact of hypertension on LE in the Japanese population, which has the highest LE worldwide. The abridged life table method was applied to calculate the LEs of both normotensive and hypertensive men and women aged 40-85 years. Hypertensive participants were categorized as having either stage 1 or stage 2 hypertension. Age-specific mortality rates across different groups were estimated using the person-year method based on the follow-up data from a representative Japanese population in a national survey (NIPPON DATA80). The proportion of hypertensive patients in the baseline survey was 50.5% for men and 41.4% for women. The LE of 40-year-old men and women was 41.7 years and 48.7 years, respectively, in normotensive participants and 39.5 and 45.8 years, respectively, in hypertensive participants. The LE difference between normotensive and hypertensive participants was 2.2 years for men and 2.9 years for women. LE decreased with increasing stages of hypertension. Similar patterns of LE, with respect to blood pressure (BP) status, were observed in all index ages and for both genders. At the population level, hypertension leads to decreased LE and affects both genders similarly. Our findings highlight the importance of preventing high BP and the consequences of hypertension in Japanese population.

摘要

预期寿命(LE)是衡量人口健康状况的指标。少数已发表的研究高血压对 LE 影响的研究主要是在西方人群中进行的。高血压对 LE 的影响在亚洲人群中尚未报道。因此,我们研究了高血压对 LE 的影响在具有全球最高 LE 的日本人群中。应用简略寿命表法计算了 40-85 岁男性和女性的正常血压和高血压人群的 LE。高血压参与者分为 1 期或 2 期高血压。根据全国调查中代表性日本人群的随访数据(NIPPON DATA80),使用人年法估计了不同组别中特定年龄的死亡率。基线调查中男性高血压患者的比例为 50.5%,女性为 41.4%。在正常血压参与者中,40 岁男性和女性的 LE 分别为 41.7 年和 48.7 年,而在高血压参与者中,LE 分别为 39.5 年和 45.8 年。男性和女性的正常血压与高血压参与者之间的 LE 差异分别为 2.2 年和 2.9 年。LE 随着高血压阶段的增加而降低。在所有指数年龄和性别中,LE 与血压(BP)状态之间存在相似的模式。在人群水平上,高血压会导致 LE 降低,并对两性产生类似的影响。我们的研究结果强调了预防高血压和高血压后果在日本人群中的重要性。

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