变形链球菌葡聚糖合成与接受含氟漱口水的学童龋齿发病率之间的关联。

Association between glucan synthesis by streptococcus mutans and caries incidence in schoolchildren receiving a fluoride mouth rinse.

作者信息

Umetsu Hidehiro, Kaneko Noboru, Yoshihara Akihiro, Sakuma Shihoko, Hanada Nobuhiro, Miyazaki Hideo

机构信息

Division on Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Nigata 951-8514, Japan.

出版信息

Oral Health Prev Dent. 2012;10(2):161-6.

PMID:22763596

Abstract

PURPOSE

To determine whether variation in glucan synthesis by Streptococcus mutans isolates is associated with caries development in children receiving a fluoride mouth rinse (FMR).

MATERIALS AND METHODS

Of 122 children (aged 9 to 10 years), 64 had received FMR (FMR(+) group) and the remaining 58 children had not (FMR(-) group). The number of decayed and filled teeth (DFT) and increases in the number of DFT in 1 year (dDFT) were recorded. Saliva samples were collected to isolate the clinical S. mutans strains. The isolates were incubated in heart infusion broth supplemented with 1% sucrose, then the amount of water-insoluble glucan (WIG) formed on a glass tube surface was evaluated.

RESULTS

In the FMR(-) group, children carrying S. mutans had a higher DFT (P = 0.039) and tended to have a higher dDFT (P = 0.080) than the others. In the FMR(+) group, although the differences between children with and without S. mutans were not significant, children carrying S. mutans that produced a high amount of WIG had higher dDFT than the other S. mutans-positive children (P = 0.034).

CONCLUSIONS

This study revealed that the variation in glucan synthesis by S. mutans is associated with caries development in children receiving a FMR.

摘要

目的

确定变形链球菌分离株葡聚糖合成的差异是否与接受含氟漱口水（FMR）的儿童龋齿发展有关。

材料与方法

122名9至10岁儿童中，64名接受了FMR（FMR(+)组），其余58名儿童未接受（FMR(-)组）。记录龋补牙数（DFT）及1年内DFT的增加数（dDFT）。收集唾液样本以分离临床变形链球菌菌株。将分离株在补充有1%蔗糖的心脏浸液肉汤中培养，然后评估在玻璃管表面形成的水不溶性葡聚糖（WIG）的量。