Somaraj Vinej, Shenoy Rekha P, Shenoy Panchmal Ganesh, Kumar Vijaya, Jodalli Praveen S, Sonde Laxminarayan
Department of Public Health Dentistry, Rajas Dental College & Hospital, Tirunelveli, Tamil Nadu, India.
Department of Public Health Dentistry, Yenepoya Dental College, Mangalore, Karnataka, India.
Int J Dent. 2017;2017:5654373. doi: 10.1155/2017/5654373. Epub 2017 Mar 2.
To assess and compare the effect of herbal and fluoride mouth rinses on count and glucan synthesis by and dental caries, a parallel group placebo controlled randomized trial was conducted among 240 schoolchildren (12-15 years old). Participants were randomly divided and allocated into Group I (0.2% fluoride group), Group II (herbal group), and Group III (placebo group). All received 10 ml of respective mouth rinses every fortnight for a period of one year. Intergroup and intragroup comparison were done for count and glucan synthesis by and dental caries. count showed a statistically significant difference between Group I and Group III ( = 0.035) and also between Group II and Group III ( = 0.039). Glucan concentration levels showed a statistically significant difference ( = 0.024) between Group II and Group III at 12th month. Mean DMF scores showed no statistical difference between the three groups ( = 0.139). No difference in the level of significance was seen in the intention-to-treat and per-protocol analysis. The present study showed that both herbal and fluoride mouth rinses, when used fortnightly, were equally effective and could be recommended for use in school-based health education program to control dental caries. Trial registration number is CTRI/2015/08/006070.
为了评估和比较草本漱口水与含氟漱口水对变形链球菌数量、葡聚糖合成及龋齿的影响，在240名12至15岁的学童中进行了一项平行组安慰剂对照随机试验。参与者被随机分为三组：第一组（0.2%含氟组）、第二组（草本组）和第三组（安慰剂组）。所有人每两周接受10毫升相应的漱口水，为期一年。对变形链球菌数量、葡聚糖合成及龋齿情况进行组间和组内比较。变形链球菌数量在第一组和第三组之间（P = 0.035）以及第二组和第三组之间（P = 0.039）显示出统计学上的显著差异。在第12个月时，葡聚糖浓度水平在第二组和第三组之间显示出统计学上的显著差异（P = 0.024）。三组的平均龋失补牙面（DMF）得分无统计学差异（P = 0.139）。在意向性分析和符合方案分析中，显著性水平没有差异。本研究表明，草本漱口水和含氟漱口水每两周使用一次时效果相同，可推荐用于学校健康教育项目以控制龋齿。试验注册号为CTRI/2015/08/006070。
