Department of haematology, University College London Hospital, London, UK.
Br J Haematol. 2012 Sep;158(6):679-90. doi: 10.1111/j.1365-2141.2012.09207.x. Epub 2012 Jul 5.
Point-of-care testing (POCT) in haematology has continued to grow in popularity and uptake throughout the world. The increasing demand to reduce the turnaround time of test results, coupled with rapid improvements in technology, have led to the development of several devices that are designed for use in different clinical settings, with the hope of improving patient care. The most used POCT in haematology is measurement of haemoglobin concentration. Other POCT devices (used primarily in developing countries) for malaria screening and CD4+ T-lymphocytes for quantification of human-immunodeficiency-virus are becoming the cornerstone for the diagnosis and management of these disorders. New devices are also available for red cell indices, white blood cell count and platelets. In this review clinical studies that validate the use of such devices will be discussed, as well as the advantages and disadvantages of POCT in haematology. A disadvantage of POCT is a lack of training, poor standardization in obtaining blood samples and insufficient internal/external quality assessment. As there is every reason to expect that POCT use will increase in all pathology disciplines, including haematology, it is imperative that systems are put in place to oversee these issues.
即时检验（POCT）在血液学领域的应用在全球范围内持续普及和应用。为了缩短检验结果的周转时间，同时结合技术的快速进步，促使开发了几种适用于不同临床环境的设备，以期改善患者的治疗效果。在血液学中最常用的 POCT 是血红蛋白浓度的测量。其他用于疟疾筛查和 CD4+T 淋巴细胞计数以定量检测人类免疫缺陷病毒的 POCT 设备（主要在发展中国家使用），正逐渐成为这些疾病诊断和管理的基石。目前也有用于红细胞指数、白细胞计数和血小板的新设备。本综述将讨论临床研究验证这些设备的应用，以及血液学 POCT 的优缺点。POCT 的缺点是缺乏培训、在获取血液样本时标准化程度差以及内部/外部质量评估不足。由于有充分的理由预计 POCT 的使用将在所有病理学领域（包括血液学）中增加，因此必须建立系统来监督这些问题。
