Parker I, Fitschen W
Experientia. 1979 Oct 15;35(10):1312-3. doi: 10.1007/BF01963978.
The activation of globin gene expression on viral transformation of 3T3 cells was investigated. Globin mRNA was determined using a radioactive complementary DNA probe. No difference was found between 3T3 and transformed 3T3 cells. There does not therefore appear to be a random activation of extensive regions of the cellular genome.
研究了3T3细胞病毒转化时珠蛋白基因表达的激活情况。使用放射性互补DNA探针测定珠蛋白mRNA。未发现3T3细胞和转化的3T3细胞之间存在差异。因此,细胞基因组的广泛区域似乎不存在随机激活。