Andoh K, Nakazato Y, Mizunuma H, Yamada K, Ibuki Y, Igarashi M
Department of Obstetrics and Gynecology, Gunma University School of Medicine, Maebashi.
Nihon Sanka Fujinka Gakkai Zasshi. 1990 Dec;42(12):1663-70.
In order to examine the accuracy of endometrial dating, endometrial dating from 52 infertile women with normal luteal function was investigated. Dating from the histological findings was evaluated from three time points, the onset of the next menstrual period (NMP), the last day of the low phase of basal body temperature (BBT) and the urinary LH peak determined with the "Organon LH Color" kit (LH). Beside microscopic observation, morphometric analysis of endometrial findings was done by means of a high speed color image analysis system "Olympus SP-500". On the day of LH Color (+2), the serum LH level showed a maximum of 35.5 +/- 12.6 mIU/ml (Mean +/- S.D.) (n = 27). The correlation coefficients for histological dating and chronological dating based on NMP, BBT and LH were 0.685, 0.728 and 0.879 in gland and 0.620, 0.737 and 0.833 in stroma, respectively. The multiple correlation coefficient for histological dating evaluated by morphometric analysis and chronological dating based on LH was 0.959. So we conclude that endometrial dating evaluated by morphometric analysis seems to be the most objective and useful.
为了检验子宫内膜日期测定的准确性，我们对52名黄体功能正常的不孕女性的子宫内膜日期测定情况进行了研究。从三个时间点评估根据组织学检查结果得出的日期，即下一次月经期（NMP）开始时、基础体温（BBT）低温期的最后一天以及使用“欧加农LH试纸”（LH）测定的尿促黄体生成素峰值。除了显微镜观察外，还通过高速彩色图像分析系统“奥林巴斯SP - 500”对子宫内膜检查结果进行形态计量分析。在LH试纸阳性日（+2），血清促黄体生成素水平最高为35.5±12.6 mIU/ml（平均值±标准差）（n = 27）。基于NMP、BBT和LH的组织学日期测定与按时间顺序的日期测定之间，腺体的相关系数分别为0.685、0.728和0.879，间质的相关系数分别为0.620、0.737和0.833。通过形态计量分析评估的组织学日期测定与基于LH的按时间顺序的日期测定之间的多重相关系数为0.959。因此我们得出结论，通过形态计量分析评估的子宫内膜日期测定似乎是最客观且有用的。
