Wang Yan, Oh Christian M, Oliveira Michael C, Islam M Shahidul, Ortega Arthur, Park B Hyle
Department of Bioengineering, University of California, Riverside, 900 University Ave., Riverside, CA 92521, USA.
Opt Express. 2012 Jul 2;20(14):14797-813. doi: 10.1364/OE.20.014797.
We present a GPU accelerated multi-functional spectral domain optical coherence tomography system at 1300 nm. The system is capable of real-time processing and display of every intensity image, comprised of 512 pixels by 2048 A-lines acquired at 20 frames per second. The update rate for all four images with size of 512 pixels by 2048 A-lines simultaneously (intensity, phase retardation, flow and en face view) is approximately 10 frames per second. Additionally, we report for the first time the characterization of phase retardation and diattenuation by a sample comprised of a stacked set of polarizing film and wave plate. The calculated optic axis orientation, phase retardation and diattenuation match well with expected values. The speed of each facet of the multi-functional OCT CPU-GPU hybrid acquisition system, intensity, phase retardation, and flow, were separately demonstrated by imaging a horseshoe crab lateral compound eye, a non-uniformly heated chicken muscle, and a microfluidic device. A mouse brain with thin skull preparation was imaged in vivo and demonstrated the capability of the system for live multi-functional OCT visualization.
我们展示了一种工作在1300纳米的GPU加速多功能光谱域光学相干断层扫描系统。该系统能够实时处理和显示每一幅强度图像，这些图像由每秒20帧采集的512像素×2048条A线组成。同时更新所有四幅大小为512像素×2048条A线的图像（强度、相位延迟、血流和表面视图）的速率约为每秒10帧。此外，我们首次报告了由一组堆叠的偏振膜和波片组成的样品的相位延迟和二向色性的特性。计算得到的光轴方向、相位延迟和二向色性与预期值匹配良好。通过对鲎的侧复眼、非均匀加热的鸡胸肉和微流控装置成像，分别展示了多功能OCT CPU-GPU混合采集系统各方面的速度，即强度、相位延迟和血流。对一只去除薄颅骨的小鼠大脑进行了活体成像，展示了该系统进行活体多功能OCT可视化的能力。
