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捷克共和国氡温泉工作人员淋巴细胞中的微核。

Micronuclei in lymphocytes from radon spa personnel in the Czech Republic.

机构信息

Department of Radiology and Toxicology, Faculty of Health and Social Studies, Southbohemian University in České Budějovice, České Budějovice, Czech Republic.

出版信息

Int Arch Occup Environ Health. 2013 Aug;86(6):629-33. doi: 10.1007/s00420-012-0795-z. Epub 2012 Jul 7.

DOI:10.1007/s00420-012-0795-z
PMID:22772398
Abstract

PURPOSE

To assess the radiation exposure of radon spa personnel in Jáchymov, Czech Republic.

METHODS

The frequency of micronucleus-containing cells and the percentage of centromere-free micronuclei (micronuclei containing only acentric fragments) was determined in peripheral blood lymphocytes of 42 individuals working at the Jáchymov spa and 42 control individuals.

RESULTS

There was a highly significant increase in the frequency of micronucleus-containing cells as well as the percentage of centromere-free micronuclei in the lymphocytes of spa personnel versus controls. No individual dosimetry data were available. A comparison with results from currently active uranium miners suggests that the individuals examined at the Jáchymov spa had accumulated effective doses in the order of several tens of mSv, very similar to those of the miners.

CONCLUSION

The spa personnel in Jáchymov needs to be monitored on an individual level.

摘要

目的

评估捷克亚希莫夫(Jáchymov)氡温泉工作人员的辐射暴露情况。

方法

测定了在雅希莫夫温泉工作的 42 名工作人员和 42 名对照个体外周血淋巴细胞中的含微核细胞的频率以及无着丝粒微核(仅含有无着丝粒片段的微核)的百分比。

结果

与对照组相比,温泉工作人员的含微核细胞的频率以及无着丝粒微核的百分比均有显著升高。没有个人剂量数据。与目前活跃的铀矿工的结果进行比较表明,在雅希莫夫温泉接受检查的个体所累积的有效剂量在几十毫希沃特(mSv)左右,与矿工非常相似。

结论

需要对雅希莫夫的温泉工作人员进行个体水平的监测。

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Mutat Res. 2010 Aug 14;701(1):80-5. doi: 10.1016/j.mrgentox.2010.05.005. Epub 2010 May 21.
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