天然产物 pederin/mycalamide 族的分离、生物活性、合成和药物化学。
Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products.
机构信息
Department of Chemistry, University of Pittsburgh, Pennsylvania 15260, USA.
出版信息
Nat Prod Rep. 2012 Sep;29(9):980-95. doi: 10.1039/c2np20052j. Epub 2012 Jul 9.
PMID:22772477
Abstract
This review highlights the broad range of science that has arisen from the isolation of pederin, the mycalamides, theopederins, and onnamides, and psymberin. Specific topics include structure determination, biological activity, synthesis, and analog preparation and analysis.
摘要
本文综述了从分离麦角酰二乙胺、麦角菌胺、海兔胺和海兔毒素以及 psymberin 中产生的广泛科学领域。具体主题包括结构测定、生物活性、合成以及类似物的制备和分析。
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