Katsouyanni K, Karakatsani A, Messari I, Touloumi G, Hatzakis A, Kalandidi A, Trichopoulos D
Department of Hygiene and Epidemiology, University of Athens Medical School, Greece.
J Epidemiol Community Health. 1990 Dec;44(4):321-4. doi: 10.1136/jech.44.4.321.
The aim was to investigate the reported association between air pollution and cause specific mortality in the city of Athens.
Cause specific mortality was contrasted between 199 d with high values of air pollution and 2*199 comparison days with low pollution, matched in a 1:2 ratio on the basis of various confounding factors. Statistical analysis was done, taking matching into account, using analysis of variance for randomised blocks.
The study was confined to the city of Athens, using data obtained between 1975 and 1982.
Cause of death was assessed in all 25 138 persons dying in the 3*199 d studied.
Causes of death were evaluated blindly by two medically qualified investigators on the basis of information in the death certificates. Mortality was generally higher during the high pollution days but the difference was more pronounced and more significant for respiratory conditions, even though the number of deaths in this category was smaller than the corresponding numbers in the other two categories examined (cardiac and "other" deaths).
The results show that the short term association between air pollution and overall mortality in Athens is likely to be causal, since it is particularly evident with respect to respiratory conditions, for which a biological air pollution link is more plausible.
旨在调查雅典市空气污染与特定病因死亡率之间所报道的关联。
将空气污染值高的199天与空气污染值低的2×199个对照日的特定病因死亡率进行对比,根据各种混杂因素按1:2的比例进行匹配。考虑到匹配因素进行了统计分析,采用随机区组方差分析。
该研究局限于雅典市,使用了1975年至1982年期间获得的数据。
对所研究的3×199天内死亡的所有25138人的死因进行了评估。
两名具有医学资质的调查人员根据死亡证明中的信息对死因进行了盲法评估。在高污染日期间死亡率总体较高,但对于呼吸道疾病,这种差异更为明显且更具显著性,尽管该类别中的死亡人数少于所检查的其他两个类别(心脏和“其他”死亡)中的相应人数。
结果表明,雅典市空气污染与总体死亡率之间的短期关联可能是因果关系,因为在呼吸道疾病方面这种关联尤为明显,而空气污染与呼吸道疾病之间的生物学联系更具合理性。