[采用¹³³Xe清除法技术测量腿部皮肤外周灌注压（SPPP）]

[Skin peripheral perfusion pressure (SPPP) in the leg using a technique of 133Xe clearance method].

作者信息

Ito H, Tanaka S, Shimada T, Isogai Y, Mori Y, Kawakami K

机构信息

Third Department of Internal Medicine, Jikei University School of Medicine, Tokyo.

出版信息

Kaku Igaku. 1990 Oct;27(10):1141-5.

PMID:2277455

Abstract

We developed a new technique for measuring skin peripheral perfusion pressure (SPPP) in the leg by 133Xe clearance method and studied the SPPP in 50 normal volunteers and 86 diabetic patients, including 16 diabetics with gangrene. The SPPP in normal subjects, diabetics without gangrene and diabetics with gangrene were 41.9 +/- 8.6 cmH2O, 30.2 +/- 12.7 cmH2O and 19.4 +/- 10.3 cmH2O, respectively. Our result revealed that the SPPP in diabetics with gangrene was significantly lowest in three groups. The decrease of the SPPP in the diabetics may be due to the steal phenomenon of the blood flow through the abnormally dilated arteriovenous shunt vessels caused by the diabetic neuropathy. The measurement of the SPPP is very useful to assess the impairment of peripheral circulation.

摘要

我们通过¹³³Xe清除法开发了一种测量腿部皮肤外周灌注压（SPPP）的新技术，并对50名正常志愿者和86名糖尿病患者（包括16名患有坏疽的糖尿病患者）的SPPP进行了研究。正常受试者、无坏疽的糖尿病患者和患有坏疽的糖尿病患者的SPPP分别为41.9±8.6 cmH₂O、30.2±12.7 cmH₂O和19.4±10.3 cmH₂O。我们的结果显示，患有坏疽的糖尿病患者的SPPP在三组中显著最低。糖尿病患者SPPP的降低可能是由于糖尿病神经病变导致血液通过异常扩张的动静脉分流血管的盗血现象。SPPP的测量对于评估外周循环障碍非常有用。