ENT Department, Guy's Hospital, London, UK.
Clin Otolaryngol. 2012 Aug;37(4):276-82. doi: 10.1111/j.1749-4486.2012.02527.x.
Review and evaluate the prevalence and severity of individual symptoms in patients with chronic rhinosinusitis (CRS) with or without nasal polyposis.
Retrospective analysis of data from the National Comparative Audit of Surgery for Nasal Polyposis and CRS, carried out across 87 hospitals in England and Wales between 2000 and 2001.
A total of 2573 patients with CRS (1784 had CRS with nasal polyposis, 789 without nasal polyposis) who had undergone sinus surgery.
Severity of clinical symptoms scores was graded on the Sino-Nasal Outcome Test 22 questionnaire. Prevalence of these symptoms and mean symptom scores were calculated for each group of patients at baseline and 3 months after surgery.
In both groups, nasal blockage/congestion had the highest mean symptom score, followed by altered smell/taste and then the need to blow nose. These three symptoms were the most prevalent in the group with nasal polyposis. In the group without nasal polyposis, nasal blockage was also the most prevalent individual symptom (93.5%) followed by altered smell/taste (75.7%). The third most prevalent symptom was waking up tired (69.9%). The average test score preoperatively was 41.5 (group with nasal polyposis) and 44.4 (group without nasal polyposis). This decreased to 18.3 and 14.1, respectively, 3 months after surgery (P < 0.001).
The leading three symptoms were nasal blockage/congestion, altered taste/smell and the need to blow the nose in terms of severity and prevalence. The total Sino-Nasal Outcome Test 22 and all individual symptom scores improved significantly after surgery.
回顾和评估伴有和不伴鼻息肉的慢性鼻-鼻窦炎(CRS)患者的个体症状的患病率和严重程度。
对 2000 年至 2001 年在英格兰和威尔士的 87 家医院进行的鼻息肉和 CRS 手术国家比较审计的数据进行回顾性分析。
共 2573 例接受鼻窦手术的 CRS 患者(1784 例伴鼻息肉,789 例不伴鼻息肉)。
使用 Sino-Nasal Outcome Test 22 问卷对临床症状严重程度评分进行分级。在基线和手术后 3 个月,计算每组患者的这些症状的患病率和平均症状评分。
在两组患者中,鼻塞/充血的平均症状评分最高,其次是嗅觉/味觉改变,然后是需要擤鼻。这三种症状在伴鼻息肉的组中最为常见。在不伴鼻息肉的组中,鼻塞也是最常见的个体症状(93.5%),其次是嗅觉/味觉改变(75.7%)。第三种最常见的症状是醒来时感到疲倦(69.9%)。术前平均测试评分分别为伴鼻息肉组 41.5 和不伴鼻息肉组 44.4。术后 3 个月分别降至 18.3 和 14.1,差异有统计学意义(P < 0.001)。
就严重程度和患病率而言,排名前三的症状是鼻塞/充血、嗅觉/味觉改变和需要擤鼻。手术后 Sino-Nasal Outcome Test 22 总分和所有个体症状评分均显著改善。