Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia.
AIDS. 2012 Jul 31;26 Suppl 1(0 1):S55-63. doi: 10.1097/QAD.0b013e3283558459.
Limited evidence is available on HIV, aging and comorbidities in sub-Saharan Africa. This article describes the prevalence of HIV and chronic comorbidities among those aged 50 years and older in South Africa using nationally representative data.
The WHO's Study of global AGEing and adult health (SAGE) was conducted in South Africa in 2007-2008. SAGE includes nationally representative cohorts of persons aged 50 years and older, with comparison samples of those aged 18-49 years, which aims to study health and its determinants.
Logistic and linear regression models were applied to data from respondents aged 50 years and older to determine associations between age, sex and HIV status and various outcome variables including prevalence of seven chronic conditions.
HIV prevalence among adults aged 50 and older in South Africa was 6.4% and was particularly elevated among Africans, women aged 50-59 and those living in rural areas. Rates of chronic disease were higher among all older adults compared with those aged 18-49. Of those aged 50 years and older, 29.6% had two or more of the seven chronic conditions compared with 8.8% of those aged 18-49 years (P < 0.0001). When controlling for age and sex among those aged 50 and older, BMI was lower among HIV-infected older adults aged 50 and older (27.5 kg/m2) than in HIV-uninfected individuals of the same age (30.6) (P < 0.0001). Grip strength among HIV-infected older adults was significantly (P=0.004) weaker than among similarly-aged HIV-uninfected individuals.
HIV-infected older adults in South Africa have high rates of chronic disease and weakness. Studies are required to examine HIV diagnostics and treatment instigation rates among older adults to ensure equity of access to quality care, as the number and percentage of older adults living with HIV is likely to increase.
有关艾滋病毒、衰老和撒哈拉以南非洲合并症的证据有限。本文使用全国代表性数据描述了南非 50 岁及以上人群中艾滋病毒和慢性合并症的流行情况。
世界卫生组织的全球老龄化和成人健康研究（SAGE）于 2007-2008 年在南非进行。SAGE 包括全国代表性的 50 岁及以上人群队列，以及 18-49 岁人群的对照样本，旨在研究健康及其决定因素。
应用逻辑回归和线性回归模型对 50 岁及以上受访者的数据进行分析，以确定年龄、性别和艾滋病毒状况与各种结果变量（包括七种慢性疾病的患病率）之间的关联。
南非 50 岁及以上成年人中艾滋病毒的流行率为 6.4%，在非洲人、50-59 岁的女性以及农村地区居民中尤其较高。与 18-49 岁人群相比，所有老年人群的慢性疾病发生率更高。在 50 岁及以上人群中，有 29.6%的人患有七种慢性疾病中的两种或两种以上，而 18-49 岁人群中这一比例为 8.8%（P<0.0001）。在控制了 50 岁及以上人群的年龄和性别后，感染艾滋病毒的老年成年人（50 岁及以上）的 BMI（27.5kg/m2）低于同年龄未感染艾滋病毒的个体（30.6kg/m2）（P<0.0001）。感染艾滋病毒的老年成年人的握力明显（P=0.004）弱于同年龄未感染艾滋病毒的个体。
南非感染艾滋病毒的老年成年人患有慢性疾病和虚弱的比率较高。需要研究老年成年人艾滋病毒诊断和治疗启动率，以确保公平获得优质护理，因为感染艾滋病毒的老年成年人的数量和比例可能会增加。
