Burden of Disease Research Unit, South African Medical Research Council, Cape Town 7505, South Africa.
School of Public Health, University of the Western Cape, Cape Town 7535, South Africa.
Int J Environ Res Public Health. 2022 Feb 18;19(4):2359. doi: 10.3390/ijerph19042359.
With improved access to antiretroviral treatment (ART), adults with HIV live longer to reach older age. The number of older adults living with HIV is increasing steadily, giving rise to a new population of interest in HIV research and for invigorated considerations in health service delivery and policy. We analysed the profile of comorbidities in older people (50 years and older) living with HIV in South Africa. We conducted a secondary analysis of all individuals over 15 years who tested HIV positive in the Fifth South African National HIV Prevalence, Incidence, Behaviour and Communication Survey, 2017. We conducted multivariate logistic regression to determine the factors associated with having HIV comorbidity using Stata 15.0 software. We entered 3755 people living with HIV into the analysis, of whom 18.3% ( = 688) were 50 years or older. Older adults had four times greater odds (OR = 4.7 (3.1-7.0)) of having an HIV comorbidity compared to younger adults. Being female (OR = 1.6 (1.1-2.4)) and living in an urban area (OR = 2.6 (1.8-3.7)) increased the odds of HIV comorbidity. Older adults with HIV require comprehensive health care to deal with multimorbidity, to maximise the benefits gained by advances in HIV therapies.
随着抗逆转录病毒治疗(ART)的普及,HIV 感染者的寿命得以延长,进入老年阶段。老年 HIV 感染者的数量稳步增加,这使得 HIV 研究的新目标人群和更有力的医疗服务提供和政策考虑成为可能。我们分析了南非老年 HIV 感染者(50 岁及以上)的合并症特征。我们对 2017 年第五次南非全国 HIV 流行率、发病率、行为和传播调查中所有检测 HIV 阳性的 15 岁以上个体进行了二次分析。我们使用 Stata 15.0 软件进行多变量逻辑回归,以确定与 HIV 合并症相关的因素。我们共纳入 3755 名 HIV 感染者进行分析,其中 18.3%(688 人)为 50 岁及以上。与年轻人相比,老年成年人发生 HIV 合并症的几率高四倍(OR=4.7(3.1-7.0))。女性(OR=1.6(1.1-2.4))和居住在城市地区(OR=2.6(1.8-3.7))会增加 HIV 合并症的发生几率。HIV 合并症的老年成年人需要全面的医疗保健,以应对多种合并症,最大限度地从 HIV 治疗的进步中获益。