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[亲属活体供肾移植]

[Transplantation of the kidney from living related donor].

作者信息

Belorusov O S, Goriaĭnov V A

出版信息

Vestn Akad Med Nauk SSSR. 1990(10):32-6.

PMID:2278181
Abstract

Ninety-nine alive related kidney donor transplantations were done in patients with terminal chronic renal failure in the Department for Transplantation of the All-Union Research Surgery Centre of USSR AMS in 1965-1989. The donors were mothers (n = 49), fathers (n = 22), sisters (n = 18), and brothers (n = 10). Donors were selected according to the criteria accepted at the Centre. To assess the degree of operative risk for the donor and the functional status of the preserved kidney, the course of the postoperative period was studied. Complications were seen in 20.2% of the donors, of which severe in 3.1%. All the complications were managed successfully and the donors were discharged quite healthy with normal blood levels of nitrogenous residues. Based on their own findings, the authors conclude that the operative risk faced by an alive related donor is insignificant, while the favourable transplantation outcomes make the risk justifiable. Besides, taking into account the deficient hemodialysis centres in this country and their poor technical equipment, the problem of alive related renal transplantation becomes especially significant.

摘要

1965年至1989年期间,苏联医学科学院全联盟研究外科中心移植科对99例终末期慢性肾衰竭患者进行了活体亲属肾移植。供体包括母亲(49例)、父亲(22例)、姐妹(18例)和兄弟(10例)。供体根据该中心认可的标准进行选择。为评估供体的手术风险程度以及保留肾脏的功能状态,对术后病程进行了研究。20.2%的供体出现并发症,其中3.1%为严重并发症。所有并发症均成功处理,供体出院时身体健康,含氮代谢产物血水平正常。基于自身研究结果,作者得出结论:活体亲属供体面临的手术风险微不足道,而良好的移植效果使这种风险具有合理性。此外,考虑到该国血液透析中心不足及其技术设备简陋,活体亲属肾移植问题变得尤为重要。

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