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镀铬工人癌症死亡率的流行病学研究。

Epidemiological study of mortality from cancer among chromium platers.

作者信息

Horiguchi S, Morinaga K, Endo G

机构信息

Department of Preventive Medicine and Environmental Health, Osaka City University Medical School, Japan.

出版信息

Asia Pac J Public Health. 1990;4(2-3):169-74. doi: 10.1177/101053959000400316.

Abstract

Cancer mortality was studied among 265 male workers in 40 small plating factories (chromium, copper and nickel) where bicycle parts are plated. The study utilized record linkage with the Osaka Cancer Registry file between January 1, 1965 and December 31, 1979. The results showed that seven workers had died of cancer, and the Standardized Mortality Ratio (SMR) calculated for all cancers, stomach cancer and lung cancer were 1.13, 1.23 and 1.11, respectively, with no significant relationship found between the observed and expected values. The SMR for lung cancer among those workers with a high degree of skin ulceration and with perforation of the nasal septum was high, 11.22 and 5.13, respectively, although not statistically significant because of the small sample size in the study. The results suggest that lung cancer occurs in those subjected to a high degree of exposure to chromium.

摘要

对40家小型电镀厂(镀铬、镀铜和镀镍)的265名男性工人进行了癌症死亡率研究,这些工厂从事自行车零部件电镀工作。该研究利用了1965年1月1日至1979年12月31日期间与大阪癌症登记处档案的记录链接。结果显示,7名工人死于癌症,所有癌症、胃癌和肺癌的标准化死亡率(SMR)分别为1.13、1.23和1.11,观察值与预期值之间未发现显著关系。皮肤溃疡程度高和鼻中隔穿孔的工人中肺癌的SMR较高,分别为11.22和5.13,尽管由于研究样本量小,差异无统计学意义。结果表明,肺癌发生在铬暴露程度高的人群中。

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