• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

患有干眼症类型病症的儿童可能报告的症状比成年患者的症状要轻。

Children with dry eye type conditions may report less severe symptoms than adult patients.

机构信息

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 166 Gumiro, Bundang-gu, Seongnam, Gyeonggi-do 463-707, Korea.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2013 Mar;251(3):791-6. doi: 10.1007/s00417-012-2097-2. Epub 2012 Jul 12.

DOI:10.1007/s00417-012-2097-2
PMID:22790310
Abstract

BACKGROUND

To compare the symptom scores of children with those of adults with the same degree of mild ocular surface signs.

METHODS

This study included patients with at least one ocular surface symptom and sign. Data obtained from 45 subjects aged 8.79 ± 2.95 yr (Mean ± SD) (pediatric group) and 45 adults aged 52.87 ± 10.87 yr (adult group) who were matched to each pediatric patient based on ocular surface signs were analyzed. Demographic data including age and sex; parameters of ocular surface signs including fluorescein staining score, tear film breakup time and Schirmer test score; symptom scores including ocular surface disease index (OSDI) and visual analog scale (VAS) were assessed and compared between the two groups.

RESULTS

Significant differences emerged in sex ratio as well as in age between the two groups (P < 0.001, for both). Regarding ocular surface signs and tear film tests, the study revealed no significant differences in fluorescein staining score (1.44 ± 1.95 vs. 1.40 ± 1.68 P = 0.913), tear film break up time (4.96 ± 1.94 vs. 3.82 ± 1.85 s, P = 0.612) and Schirmer score (12.79 ± 9.05 vs. 10.11 ± 8.45 mm / 5 min, P = 0.370). Regarding dry eye symptoms, both OSDI and VAS were significantly lower in the pediatric group (P = 0.001 and < 0.001, respectively) than in the adult group.

CONCLUSION

Pediatric patients with mild ocular surface damage may report fewer dry eye symptoms compared to adult patients with similar stages of ocular surface damage.

摘要

背景

比较具有相同轻度眼表体征的儿童与成人的症状评分。

方法

本研究纳入至少存在一项眼表症状和体征的患者。对 45 名年龄 8.79±2.95 岁(均值±标准差)(儿科组)和 45 名年龄 52.87±10.87 岁(成人组)的患者进行了数据分析,这些患者均根据眼表体征与每例儿科患者相匹配。评估并比较了两组患者的人口统计学数据(包括年龄和性别);眼表体征参数(包括荧光素染色评分、泪膜破裂时间和泪液分泌试验);症状评分(包括眼表疾病指数和视觉模拟评分)。

结果

两组患者的性别比例和年龄均存在显著差异(均 P<0.001)。关于眼表体征和泪膜检查,研究发现荧光素染色评分(1.44±1.95 比 1.40±1.68,P=0.913)、泪膜破裂时间(4.96±1.94 比 3.82±1.85 s,P=0.612)和 Schirmer 评分(12.79±9.05 比 10.11±8.45 mm/5 min,P=0.370)均无显著差异。在干眼症状方面,儿科组的眼表疾病指数和视觉模拟评分均显著低于成人组(P=0.001 和<0.001)。

结论

与具有相似眼表损伤程度的成人患者相比,轻度眼表损伤的儿科患者可能报告更少的干眼症状。

相似文献

1
Children with dry eye type conditions may report less severe symptoms than adult patients.患有干眼症类型病症的儿童可能报告的症状比成年患者的症状要轻。
Graefes Arch Clin Exp Ophthalmol. 2013 Mar;251(3):791-6. doi: 10.1007/s00417-012-2097-2. Epub 2012 Jul 12.
2
Correlation of tear fluorescein clearance and Schirmer test scores with ocular irritation symptoms.泪液荧光素清除率及泪液分泌试验评分与眼刺激症状的相关性
Ophthalmology. 1999 Apr;106(4):803-10. doi: 10.1016/S0161-6420(99)90170-7.
3
Comparison of ocular surface disease index and tear osmolarity as markers of ocular surface dysfunction in video terminal display workers.视频终端显示作业人员眼表功能障碍的眼表疾病指数和泪液渗透压标志物比较。
Am J Ophthalmol. 2014 Jul;158(1):41-48.e2. doi: 10.1016/j.ajo.2014.03.007. Epub 2014 Mar 13.
4
A standardized visual scale for evaluation of tear fluorescein clearance.一种用于评估泪液荧光素清除率的标准化视觉量表。
Ophthalmology. 2000 Jul;107(7):1338-43. doi: 10.1016/s0161-6420(00)00101-9.
5
Tear function and ocular surface findings in premature and term babies.早产儿和足月儿的泪液功能及眼表检查结果
Ophthalmology. 2004 May;111(5):901-5. doi: 10.1016/j.ophtha.2003.07.017.
6
Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome.原发性干燥综合征患者全身活动指数与干眼严重程度之间的关联
Arq Bras Oftalmol. 2019 Jan-Feb;82(1):45-50. doi: 10.5935/0004-2749.20190005. Epub 2018 Nov 1.
7
Evaluation of ocular surface damage and dry eye status in chronic hepatitis C at different stages of hepatic fibrosis.评估不同纤维化阶段慢性丙型肝炎患者的眼表损伤和干眼症状态。
Cornea. 2009 Oct;28(9):997-1002. doi: 10.1097/ICO.0b013e3181a0a3c5.
8
Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface.准分子原位角膜磨镶术对泪液分泌、清除及眼表的影响。
Ophthalmology. 2001 Jul;108(7):1230-5. doi: 10.1016/s0161-6420(01)00623-6.
9
Automated Measurement of Tear Film Dynamics and Lipid Layer Thickness for Assessment of Non-Sjögren Dry Eye Syndrome With Meibomian Gland Dysfunction.用于评估伴有睑板腺功能障碍的非干燥综合征干眼综合征的泪膜动力学和脂质层厚度的自动测量
Cornea. 2017 Feb;36(2):176-182. doi: 10.1097/ICO.0000000000001101.
10
Correlation of the Schirmer 1 and fluorescein clearance tests with the severity of corneal epithelial and eyelid disease.泪液分泌试验1和荧光素清除试验与角膜上皮及眼睑疾病严重程度的相关性。
Arch Ophthalmol. 2000 Dec;118(12):1632-8. doi: 10.1001/archopht.118.12.1632.

引用本文的文献

1
Emerging Age-Specific Therapeutic Approaches for Dry Eye Disease.针对干眼症的新兴年龄特异性治疗方法。
J Clin Med. 2025 Jun 11;14(12):4147. doi: 10.3390/jcm14124147.
2
Refractive Surgery in Myopic Children.近视儿童的屈光手术
J Clin Med. 2024 Jul 24;13(15):4311. doi: 10.3390/jcm13154311.
3
Alterations in the tear film and ocular surface in pediatric migraine patients.儿童偏头痛患者泪膜和眼表的改变。

本文引用的文献

1
Prevalence of dry eye disease in an elderly Korean population.韩国老年人群中干眼病的患病率。
Arch Ophthalmol. 2011 May;129(5):633-8. doi: 10.1001/archophthalmol.2011.78.
2
Dry eye in pediatric contact lens wearers.儿童隐形眼镜佩戴者的干眼症。
Eye Contact Lens. 2010 Nov;36(6):352-5. doi: 10.1097/ICL.0b013e3181f8bc25.
3
Reduced corneal sensitivity in patients with primary Sjögren's syndrome.原发性干燥综合征患者角膜敏感性降低。
Indian J Ophthalmol. 2024 Nov 1;72(11):1618-1623. doi: 10.4103/IJO.IJO_2594_23. Epub 2024 May 20.
4
Differential Impact of 0.01% and 0.05% Atropine Eyedrops on Ocular Surface in Young Adults.0.01%和 0.05%阿托品滴眼液对青年人群眼表的影响差异。
Transl Vis Sci Technol. 2024 Apr 2;13(4):22. doi: 10.1167/tvst.13.4.22.
5
Characteristics of the Ocular Surface in Myopic Child Candidates of Orthokeratology Lens Wear.角膜塑形镜佩戴近视儿童候选者的眼表特征
Ophthalmol Ther. 2023 Dec;12(6):3067-3079. doi: 10.1007/s40123-023-00793-y. Epub 2023 Sep 4.
6
Symptoms and signs of dry eye in children with Graves' ophthalmopathy.格雷夫斯眼病患儿干眼症的症状和体征。
Saudi J Ophthalmol. 2023 Feb 17;37(2):149-153. doi: 10.4103/sjopt.sjopt_47_22. eCollection 2023 Apr-Jun.
7
Evaluation of dry eyes in children with vernal kerato-conjunctivitis using clinical tests and ocular surface analysis.评估儿童春季角结膜炎的干眼情况:临床检查与眼表分析。
Indian J Ophthalmol. 2023 Apr;71(4):1488-1494. doi: 10.4103/IJO.IJO_2836_22.
8
Pediatric chronic graft-versus-host disease-related dry eye disease and the diagnostic association of potential clinical findings.儿童慢性移植物抗宿主病相关干眼疾病与潜在临床发现的诊断关联。
Sci Rep. 2023 Mar 2;13(1):3575. doi: 10.1038/s41598-023-30288-6.
9
The Incidence and Risk Factors for Dry Eye After Pediatric Strabismus Surgery.小儿斜视手术后干眼症的发病率及危险因素
Ophthalmol Ther. 2023 Feb;12(1):87-98. doi: 10.1007/s40123-022-00590-z. Epub 2022 Oct 13.
10
Evaluation of the meibomian glands using the tear interferometer wearing orthokeratology lenses.使用角膜塑形镜评估泪膜干涉仪的麦氏腺。
BMC Ophthalmol. 2022 Mar 24;22(1):133. doi: 10.1186/s12886-022-02365-3.
Acta Ophthalmol. 2010 Nov;88(7):e277-8. doi: 10.1111/j.1755-3768.2009.01693.x.
4
Dry eye in childhood: epidemiological and clinical aspects.儿童干眼症:流行病学与临床方面
Ocul Surf. 2008 Jan;6(1):44-51. doi: 10.1016/s1542-0124(12)70104-0.
5
Keratoconjunctivitis sicca in juvenile rheumatoid arthritis.青少年类风湿关节炎伴发的干燥性角结膜炎
Cornea. 2007 Sep;26(8):941-4. doi: 10.1097/ICO.0b013e3180de1f34.
6
Management of dry eye related to systemic diseases in childhood and longterm follow-up.儿童期与全身性疾病相关的干眼管理及长期随访
Acta Ophthalmol Scand. 2007 Nov;85(7):739-44. doi: 10.1111/j.1600-0420.2007.00934.x. Epub 2007 Jun 8.
7
Research in dry eye: report of the Research Subcommittee of the International Dry Eye WorkShop (2007).干眼研究:国际干眼研讨会研究小组委员会报告(2007年)
Ocul Surf. 2007 Apr;5(2):179-93. doi: 10.1016/s1542-0124(12)70086-1.
8
Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye WorkShop (2007).干眼症的管理与治疗:国际干眼症研讨会管理与治疗小组委员会报告(2007年)
Ocul Surf. 2007 Apr;5(2):163-78. doi: 10.1016/s1542-0124(12)70085-x.
9
The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007).干眼病的流行病学:国际干眼病研讨会流行病学小组委员会报告(2007年)
Ocul Surf. 2007 Apr;5(2):93-107. doi: 10.1016/s1542-0124(12)70082-4.
10
Prevalence of dry eye in Bangkok, Thailand.泰国曼谷干眼症的患病率。
Cornea. 2006 Dec;25(10):1162-7. doi: 10.1097/01.ico.0000244875.92879.1a.