Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 166 Gumiro, Bundang-gu, Seongnam, Gyeonggi-do 463-707, Korea.
Graefes Arch Clin Exp Ophthalmol. 2013 Mar;251(3):791-6. doi: 10.1007/s00417-012-2097-2. Epub 2012 Jul 12.
To compare the symptom scores of children with those of adults with the same degree of mild ocular surface signs.
This study included patients with at least one ocular surface symptom and sign. Data obtained from 45 subjects aged 8.79 ± 2.95 yr (Mean ± SD) (pediatric group) and 45 adults aged 52.87 ± 10.87 yr (adult group) who were matched to each pediatric patient based on ocular surface signs were analyzed. Demographic data including age and sex; parameters of ocular surface signs including fluorescein staining score, tear film breakup time and Schirmer test score; symptom scores including ocular surface disease index (OSDI) and visual analog scale (VAS) were assessed and compared between the two groups.
Significant differences emerged in sex ratio as well as in age between the two groups (P < 0.001, for both). Regarding ocular surface signs and tear film tests, the study revealed no significant differences in fluorescein staining score (1.44 ± 1.95 vs. 1.40 ± 1.68 P = 0.913), tear film break up time (4.96 ± 1.94 vs. 3.82 ± 1.85 s, P = 0.612) and Schirmer score (12.79 ± 9.05 vs. 10.11 ± 8.45 mm / 5 min, P = 0.370). Regarding dry eye symptoms, both OSDI and VAS were significantly lower in the pediatric group (P = 0.001 and < 0.001, respectively) than in the adult group.
Pediatric patients with mild ocular surface damage may report fewer dry eye symptoms compared to adult patients with similar stages of ocular surface damage.
比较具有相同轻度眼表体征的儿童与成人的症状评分。
本研究纳入至少存在一项眼表症状和体征的患者。对 45 名年龄 8.79±2.95 岁(均值±标准差)(儿科组)和 45 名年龄 52.87±10.87 岁(成人组)的患者进行了数据分析,这些患者均根据眼表体征与每例儿科患者相匹配。评估并比较了两组患者的人口统计学数据(包括年龄和性别);眼表体征参数(包括荧光素染色评分、泪膜破裂时间和泪液分泌试验);症状评分(包括眼表疾病指数和视觉模拟评分)。
两组患者的性别比例和年龄均存在显著差异(均 P<0.001)。关于眼表体征和泪膜检查,研究发现荧光素染色评分(1.44±1.95 比 1.40±1.68,P=0.913)、泪膜破裂时间(4.96±1.94 比 3.82±1.85 s,P=0.612)和 Schirmer 评分(12.79±9.05 比 10.11±8.45 mm/5 min,P=0.370)均无显著差异。在干眼症状方面,儿科组的眼表疾病指数和视觉模拟评分均显著低于成人组(P=0.001 和<0.001)。
与具有相似眼表损伤程度的成人患者相比,轻度眼表损伤的儿科患者可能报告更少的干眼症状。