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粪肠球菌NKR-5-3是一种多种细菌素产生菌，鉴定其产生的新型IIa类细菌素肠球菌素NKR-5-3C。

Identification of enterocin NKR-5-3C, a novel class IIa bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3.

作者信息

Himeno Kohei, Fujita Koji, Zendo Takeshi, Wilaipun Pongtep, Ishibashi Naoki, Masuda Yoshimitsu, Yoneyama Fuminori, Leelawatcharamas Vichien, Nakayama Jiro, Sonomoto Kenji

机构信息

Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, Fukuoka, Japan.

出版信息

Biosci Biotechnol Biochem. 2012;76(6):1245-7. doi: 10.1271/bbb.120089. Epub 2012 Jun 7.

DOI:10.1271/bbb.120089
PMID:22790957
Abstract

The structure of enterocin NKR-5-3C, an anti-listerial bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3, was determined. Enterocin NKR-5-3C is a novel class IIa bacteriocin that possesses an YGNGL motif sequence and two disulfide bridges in its structure. It is encoded on gene ent53C together with an 18-amino-acid-residue double glycine leader peptide.

摘要

确定了由多重细菌素产生菌粪肠球菌NKR-5-3产生的抗李斯特菌细菌素肠球菌素NKR-5-3C的结构。肠球菌素NKR-5-3C是一种新型的IIa类细菌素，其结构中具有YGNGL基序序列和两个二硫键。它与一个18个氨基酸残基的双甘氨酸前导肽一起编码在ent53C基因上。

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