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卡梅伦病变:大型食管裂孔疝患者缺铁性贫血的一个常被忽视的原因。

Cameron lesions: an often overlooked cause of iron deficiency anaemia in patients with large hiatal hernias.

作者信息

Kimer Nina, Schmidt Palle Nordblad, Krag Aleksander

机构信息

Department of Gastroenterology, Copenhagen University Hospital, Hvidovre, Denmark.

出版信息

BMJ Case Rep. 2010 Oct 28;2010:bcr0620103129. doi: 10.1136/bcr.06.2010.3129.

DOI:10.1136/bcr.06.2010.3129
PMID:22791730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3029377/
Abstract

Cameron lesions are linear gastric ulcers or erosions on the mucosal folds at the diaphragmatic impression in patients with a large hiatal hernia. The lesions are associated with occult bleeding and development of chronic iron deficiency anaemia, but are often overlooked during routine endoscopy. We present two patients with known hiatal hernias in who repeated endoscopic examinations had not been able to identify a source of bleeding. In both cases, typical Cameron lesions were found either by repeat gastroscopy or by capsule endoscopy. Treatment with high-dose proton pump inhibitor and iron supplement was initiated.

摘要

卡梅伦病变是指患有巨大食管裂孔疝的患者在膈肌压迹处黏膜皱襞上出现的线性胃溃疡或糜烂。这些病变与隐匿性出血及慢性缺铁性贫血的发生有关,但在常规内镜检查中常被忽视。我们报告了两名已知患有食管裂孔疝的患者,其反复内镜检查均未能发现出血源。在这两例病例中,通过重复胃镜检查或胶囊内镜检查均发现了典型的卡梅伦病变。随后开始使用高剂量质子泵抑制剂和铁剂进行治疗。

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