Ophthalmology Department, Peking University 3rd Hospital, Peking University Eye Center, and Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China.
PLoS One. 2012;7(7):e39340. doi: 10.1371/journal.pone.0039340. Epub 2012 Jul 9.
Transscleral retinal photocoagulation with a diode laser is used in glaucoma refractory to medical and surgical treatment. Our main research question was how the technique performed in large vascular lesions associated with hemangiomas of the retina and choroid.
METHODOLOGY/CLINICAL FINDINGS: Patient charts were retrieved from the hospital files for patients who underwent the procedure and were followed for at least 24 months. Five patients (6 eyes) fit the criteria. Cases included Von Hippel's disease (2 eyes), Coats' disease (1 eye) and choroidal hemangioma (3 cases). Transscleral diode laser treatment was performed under retrobulbar and topical anesthesia with a retinopexy probe (IRIS DioPexy, IRIS Medical Instruments, Mountain View, CA) applied transsclerally under indirect ophthalmoscope visualization. We found an improvement in best-corrected visual acuity at 24 months postoperatively.
CONCLUSIONS/SIGNIFICANCE: Transscleral photocoagulation may have a clinical application in these diseases as an alternate to the high cost of photodynamic therapy with photosensitizing agents.
二极管激光经巩膜视网膜光凝术用于治疗药物和手术治疗无效的青光眼。我们的主要研究问题是该技术在与视网膜和脉络膜血管瘤相关的大血管病变中的表现。
方法/临床发现:从医院档案中检索出接受该手术并至少随访 24 个月的患者病历。符合标准的患者有 5 名(6 只眼)。病例包括 Von Hippel 病(2 只眼)、Coats 病(1 只眼)和脉络膜血管瘤(3 例)。在球后和局部麻醉下使用视网膜固定探针(IRIS DioPexy,IRIS Medical Instruments,Mountain View,CA),在间接检眼镜下进行经巩膜应用,进行经巩膜二极管激光治疗。我们发现术后 24 个月最佳矫正视力有所改善。
结论/意义:与光敏剂的光动力疗法相比,经巩膜光凝术可能在这些疾病中有临床应用,因为其成本较高。