2009/10 年和 2010/11 年流感季节丹麦重症监护病房中甲型和乙型流感的负担和特征。
Burden and characteristics of influenza A and B in Danish intensive care units during the 2009/10 and 2010/11 influenza seasons.
机构信息
European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control, Artillerivej 5, Stockholm, Sweden.
出版信息
Epidemiol Infect. 2013 Apr;141(4):767-75. doi: 10.1017/S0950268812001471. Epub 2012 Jul 16.
Abstract
Influenza surveillance in Danish intensive care units (ICUs) was performed during the 2009/10 and 2010/11 influenza seasons to monitor the burden on ICUs. All 44 Danish ICUs reported aggregate data for incidence and point prevalence, and case-based demographical and clinical parameters. Additional data on microbiological testing, vaccination and death were obtained from national registers. Ninety-six patients with influenza A(H1N1)pdm09 were recorded in 2009/10; 106 with influenza A and 42 with influenza B in 2010/11. The mean age of influenza A patients was higher in 2010/11 than in 2009/10, 53 vs. 44 years (P = 0·004). No differences in other demographic and clinical parameters were detected between influenza A and B patients. In conclusion, the number of patients with severe influenza was higher in Denmark during the 2010/11 than the 2009/10 season with a shift towards older age groups in influenza A patients. Influenza B caused severe illness and needs consideration in clinical and public health policy.
摘要
丹麦的重症监护病房（ICUs）在 2009/10 和 2010/11 流感季节进行了流感监测，以监测 ICU 的负担。所有 44 家丹麦 ICU 报告了发病率和时点患病率的综合数据，以及基于病例的人口统计学和临床参数。从国家登记处获得了关于微生物检测、疫苗接种和死亡的其他数据。2009/10 年记录了 96 例甲型 H1N1pdm09 流感患者；2010/11 年有 106 例甲型流感和 42 例乙型流感。2010/11 年甲型流感患者的平均年龄高于 2009/10 年，分别为 53 岁和 44 岁（P=0.004）。甲型和乙型流感患者的其他人口统计学和临床参数无差异。总之，丹麦 2010/11 年的严重流感患者人数高于 2009/10 年，且甲型流感患者的年龄组有所增加。乙型流感可引起严重疾病，在临床和公共卫生政策中需要考虑。
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