Ako-Nai A K, Taiwo O, Ebri A, Adeniran M O
Department of Microbiology, Obafemi Awolowo University, Ile-lfe, Nigeria.
East Afr Med J. 1990 Jun;67(6):407-12.
Of the nine hundred and twenty patients clinically diagnosed of having septicaemia at the Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria between 1980-1987, 233 (25.3%) had blood samples positive by culture. Thirteen different bacterial species were identified from positive blood cultures of which six predominated: Staphylococcus aureus (30.5%), Coliforms (17.6%), Klebsiella spp. (14.2%), Pseudomonas aeruginosa (9.2%), Escherichia coli (7.9%) and Salmonella typhi (5.9%). The in vitro antibiotic, disc sensitivity pattern of the isolates showed they were relatively resistant to ampicillin and penicillin G but comparatively sensitive to antibiotics commonly used in the treatment of infections caused by these organisms. Septicaemia cases were recorded in all age groups but incidence in females was slightly but not significantly higher than in males (p less than 0.05). The study reveals the predominance of S. aureus strains in case of septicaemia in Nigeria.
1980年至1987年期间，在尼日利亚伊费市奥巴费米·阿沃洛沃大学教学医院综合院区，临床诊断为败血症的920例患者中，有233例（25.3%）血培养样本呈阳性。从阳性血培养物中鉴定出13种不同的细菌种类，其中6种占主导：金黄色葡萄球菌（30.5%）、大肠菌群（17.6%）、克雷伯菌属（14.2%）、铜绿假单胞菌（9.2%）、大肠杆菌（7.9%）和伤寒沙门氏菌（5.9%）。分离株的体外抗生素纸片药敏模式显示，它们对氨苄西林和青霉素G相对耐药，但对常用于治疗由这些微生物引起的感染的抗生素相对敏感。各年龄组均有败血症病例记录，但女性发病率略高于男性，但差异无统计学意义（p<0.05）。该研究揭示了在尼日利亚败血症病例中金黄色葡萄球菌菌株占主导地位。
