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孟加拉国类鼻疽伯克霍尔德菌的血清流行病学监测。

Seroepidemiological surveillance of Burkholderia pseudomallei in Bangladesh.

机构信息

Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, 3/F, 60th Anniversary Chalermprakiat Bldg, 420/6 Rajvithi Road, Rajathevi, Bangkok 10400, Thailand.

出版信息

Trans R Soc Trop Med Hyg. 2012 Sep;106(9):576-8. doi: 10.1016/j.trstmh.2012.06.003. Epub 2012 Jul 15.

DOI:10.1016/j.trstmh.2012.06.003
PMID:22795754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3424416/
Abstract

Melioidosis (Burkholderia pseudomallei infection) has yet to be demonstrated systematically in Bangladesh. A prospective, cross-sectional serological survey was conducted in 2010 at six Bangladeshi hospitals. Age, gender, occupation and residential address were recorded. Of 1244 patients, 359 (28.9%) were positive for B. pseudomallei by indirect haemagglutination assay. Farmers had an increased risk of seropositivity (risk ratio=1.4, 95% CI 1.0-1.8; p=0.03). There was no clear geographic clustering of seropositives. Melioidosis should be considered as a possible cause of febrile illness in Bangladesh. Further studies are needed to establish the incidence of clinical disease and distribution of environmental risk.

摘要

在孟加拉国,类鼻疽(伯克霍尔德氏菌感染)尚未得到系统证实。2010 年在孟加拉国的六家医院进行了一项前瞻性、横断面血清学调查。记录了年龄、性别、职业和居住地址。在 1244 名患者中,359 名(28.9%)通过间接血凝试验呈布氏杆菌假单胞菌阳性。农民的血清阳性率有增加的风险(风险比=1.4,95%可信区间 1.0-1.8;p=0.03)。血清阳性者没有明显的地理聚集性。在孟加拉国,类鼻疽应被视为发热性疾病的一个可能原因。需要进一步研究以确定临床疾病的发病率和环境风险的分布。

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本文引用的文献

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Imported melioidosis with an isolated cutaneous presentation in a 90-year-old traveller from Bangladesh.一名来自孟加拉国的90岁旅行者出现孤立性皮肤表现的输入性类鼻疽病。
Bull Soc Pathol Exot. 2007 Feb;100(1):22-5.
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Short report: Melioidosis in Myanmar: forgotten but not gone?简短报告:缅甸的类鼻疽:被遗忘但未消失?
Am J Trop Med Hyg. 2006 Nov;75(5):945-6.
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Melioidosis: epidemiology, pathophysiology, and management.类鼻疽病:流行病学、病理生理学及管理
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Serological diagnosis of human melioidosis with indirect hemagglutination and complement fixation tests.采用间接血凝试验和补体结合试验对人类类鼻疽进行血清学诊断。
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