在热带澳大利亚达尔文地区，类鼻疽高度流行，然而在接触过伯克霍尔德菌的健康成年人中，该菌的血清阳性率却出奇地低。
Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic.
作者信息
James Gemma L, Delaney Ben, Ward Linda, Freeman Kevin, Mayo Mark, Currie Bart J
机构信息
Emergency Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
出版信息
Clin Vaccine Immunol. 2013 May;20(5):759-60. doi: 10.1128/CVI.00021-13. Epub 2013 Mar 27.
Abstract
In the Darwin region of Australia where melioidosis is highly endemic, only 11/354 (3%) healthy residents were seropositive by indirect hemagglutination assay, despite extensive exposure to Burkholderia pseudomallei. None developed melioidosis, but some described a prior self-limiting illness. This seropositivity rate is much lower than that seen in northeast Thailand, where melioidosis is similarly highly endemic, potentially reflecting important differences between these two locations in the epidemiology of melioidosis.
摘要
在澳大利亚的达尔文地区，类鼻疽高度流行，尽管居民广泛接触到类鼻疽杆菌，但通过间接血凝试验检测，354名健康居民中只有11人（3%）血清呈阳性。没有人患上类鼻疽，但有些人描述曾患过一种自限性疾病。这一血清阳性率远低于泰国东北部，那里类鼻疽同样高度流行，这可能反映了这两个地区在类鼻疽流行病学方面的重要差异。
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