Molecular Physiology Group, The August Krogh Centre, Department of Exercise and Sport Sciences, University of Copenhagen, Denmark.
Mol Cell Endocrinol. 2013 Feb 25;366(2):204-14. doi: 10.1016/j.mce.2012.06.013. Epub 2012 Jul 11.
The energy/fuel sensor 5'-AMP-activated protein kinase (AMPK) is viewed as a master regulator of cellular energy balance due to its many roles in glucose, lipid, and protein metabolism. In this review we focus on the regulation of AMPK activity in skeletal muscle and its involvement in glucose metabolism, including glucose transport and glycogen synthesis. In addition, we discuss the plausible interplay between AMPK and insulin signaling regulating these processes.
能量/燃料传感器 5'- 腺苷酸活化蛋白激酶（AMPK）因其在葡萄糖、脂质和蛋白质代谢中的多种作用，被视为细胞能量平衡的主要调节因子。在这篇综述中，我们重点讨论了骨骼肌中 AMPK 活性的调节及其在葡萄糖代谢中的作用，包括葡萄糖转运和糖原合成。此外，我们还讨论了 AMPK 和胰岛素信号调节这些过程的可能相互作用。
