• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Is it time to replace the tuberculin skin test with a blood test?

作者信息

LoBue Philip A, Castro Kenneth G

机构信息

Division of Tuberculosis Elimination, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E-10, Atlanta, GA 30333, USA.

出版信息

JAMA. 2012 Jul 18;308(3):241-2. doi: 10.1001/jama.2012.7511.

DOI:10.1001/jama.2012.7511
PMID:22797639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4629850/
Abstract
摘要

相似文献

1
Is it time to replace the tuberculin skin test with a blood test?是时候用血液检测取代结核菌素皮肤试验了吗？
JAMA. 2012 Jul 18;308(3):241-2. doi: 10.1001/jama.2012.7511.
2
[Comparison of interferon-gamma whole blood assay with tuberculin skin test for the diagnosis of tuberculosis infection in tuberculosis contacts].[γ-干扰素全血检测与结核菌素皮肤试验用于诊断结核病接触者结核感染的比较]
Mikrobiyol Bul. 2007 Apr;41(2):193-202.
3
Profile of interferon-gamma response to latency-associated and novel in vivo expressed antigens in a cohort of subjects recently exposed to Mycobacterium tuberculosis.近期接触过结核分枝杆菌的一组受试者中，γ干扰素对潜伏相关及体内新表达抗原的反应概况
Tuberculosis (Edinb). 2015 Dec;95(6):751-757. doi: 10.1016/j.tube.2015.08.002. Epub 2015 Sep 1.
4
Differential positive TSPOT assay responses to ESAT-6 and CFP-10 in health care workers.医护人员对ESAT-6和CFP-10的TSPOT检测阳性反应差异
Tuberculosis (Edinb). 2016 Dec;101S:S83-S91. doi: 10.1016/j.tube.2016.09.012. Epub 2016 Sep 28.
5
[Advances in the diagnosis of latent tuberculosis infection in patients receiving renal replacement therapy].[接受肾脏替代治疗患者潜伏性结核感染的诊断进展]
Nefrologia. 2011;31(2):137-41. doi: 10.3265/Nefrologia.pre2011.Feb.10823.
6
Evaluation of an interferon gamma assay in the diagnosis of latent tuberculosis infection in patients with rheumatoid arthritis.评价干扰素γ检测在类风湿关节炎患者潜伏结核感染诊断中的价值。
Rheumatol Int. 2009 Nov;30(1):57-62. doi: 10.1007/s00296-009-0910-y.
7
Positive conversion of tuberculin skin test and performance of interferon release assay to detect hidden tuberculosis infection during anti-tumor necrosis factor agent trial.在抗肿瘤坏死因子药物试验期间，结核菌素皮肤试验和干扰素释放试验对潜伏性结核感染的阳性转化。
J Rheumatol. 2009 Oct;36(10):2158-63. doi: 10.3899/jrheum.090150. Epub 2009 Sep 1.
8
Prospective comparison of tuberculin skin test and QuantiFERON-TB Gold In-Tube assay for the detection of latent tuberculosis infection among healthcare workers in a low-incidence setting.在低发病环境中，对医护人员进行潜伏性结核感染检测的结核菌素皮肤试验与 QuantiFERON-TB Gold In-Tube 检测的前瞻性比较。
Infect Control Hosp Epidemiol. 2009 Nov;30(11):1123-6. doi: 10.1086/644754.
9
Concordance of a positive tuberculin skin test and an interferon gamma release assay in bacille Calmette-Guérin vaccinated persons.卡介苗接种者中结核菌素皮肤试验阳性与干扰素γ释放试验的一致性。
Int J Tuberc Lung Dis. 2011 Feb;15(2):174-8, i.
10
Interferon-γ release assays or tuberculin skin test for detection and management of latent tuberculosis infection: a systematic review and meta-analysis.干扰素-γ 释放试验或结核菌素皮肤试验用于潜伏性结核感染的检测和管理：系统评价和荟萃分析。
Lancet Infect Dis. 2020 Dec;20(12):1457-1469. doi: 10.1016/S1473-3099(20)30276-0. Epub 2020 Jul 13.

引用本文的文献

1
High Immunogenicity of a T-Cell Epitope-Rich Recombinant Protein Rv1566c-444 From in Immunized BALB/c Mice, Despite Its Low Diagnostic Sensitivity.尽管 Rv1566c-444 重组蛋白的诊断敏感性较低，但在免疫的 BALB/c 小鼠中具有高免疫原性。
Front Immunol. 2022 Feb 21;13:824415. doi: 10.3389/fimmu.2022.824415. eCollection 2022.
2
Elevated Rates of Indeterminate Results on QuantiFERON-TB Gold Plus in COVID-19 Patients.新冠肺炎患者中结核感染 T 细胞检测试剂盒（酶联免疫斑点法）检测结果不确定率升高。
J Clin Microbiol. 2021 Sep 20;59(10):e0141421. doi: 10.1128/JCM.01414-21. Epub 2021 Aug 4.
3
Heme Oxygenase-1 as a Pharmacological Target for Host-Directed Therapy to Limit Tuberculosis Associated Immunopathology.血红素加氧酶-1作为宿主导向疗法的药理学靶点以限制结核病相关免疫病理学
Antioxidants (Basel). 2021 Jan 26;10(2):177. doi: 10.3390/antiox10020177.
4
The positive tuberculin test is not synonymous with latent tuberculosis.结核菌素试验阳性并不等同于潜伏性结核。
Rev Esp Sanid Penit. 2019;21(2):111-112.
5
Pharmacist perceptions of the New Mexico pharmacist-performed tuberculosis testing program.药剂师对新墨西哥州药剂师实施的结核病检测项目的看法。
J Am Pharm Assoc (2003). 2018 Nov-Dec;58(6):647-651. doi: 10.1016/j.japh.2018.08.010. Epub 2018 Sep 28.
6
Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae.维生素 D 状态有助于巨噬细胞对抗麻风分枝杆菌的抗菌活性。
PLoS Negl Trop Dis. 2018 Jul 2;12(7):e0006608. doi: 10.1371/journal.pntd.0006608. eCollection 2018 Jul.
7
Screening of latent tuberculosis infection among health care workers working in Hajj pilgrimage area in Saudi Arabia, using interferon gamma release assay and tuberculin skin test.使用干扰素γ释放试验和结核菌素皮肤试验对在沙特阿拉伯朝觐地区工作的医护人员进行潜伏性结核感染筛查。
Ann Saudi Med. 2018 Mar-Apr;38(2):90-96. doi: 10.5144/0256-4947.2018.90.
8
Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection.对QuantiFERON检测上清液进行高度多重蛋白质组学分析以鉴定潜伏性结核感染的生物标志物。
J Clin Microbiol. 2017 Feb;55(2):391-402. doi: 10.1128/JCM.01646-16. Epub 2016 Nov 16.
9
Interferon-gamma release assay versus tuberculin skin test for latent tuberculosis infection among HIV patients in Brazil.巴西HIV患者中用于潜伏性结核感染检测的干扰素-γ释放试验与结核菌素皮肤试验的比较
Braz J Infect Dis. 2016 Jan-Feb;20(1):69-75. doi: 10.1016/j.bjid.2015.10.007. Epub 2015 Dec 17.
10
Combined antigen-specific interferon-γ and interleukin-2 release assay (FluoroSpot) for the diagnosis of Mycobacterium tuberculosis infection.联合抗原特异性干扰素-γ和白细胞介素-2释放试验（荧光斑点法）用于诊断结核分枝杆菌感染。
PLoS One. 2015 Mar 18;10(3):e0120006. doi: 10.1371/journal.pone.0120006. eCollection 2015.

本文引用的文献

1
Modelling tuberculosis trends in the USA.美国结核病趋势建模。
Epidemiol Infect. 2012 Oct;140(10):1862-72. doi: 10.1017/S095026881100286X. Epub 2012 Jan 11.
2
Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis.γ-干扰素释放试验对新发活动性肺结核的预测价值：系统评价和荟萃分析。
Lancet Infect Dis. 2012 Jan;12(1):45-55. doi: 10.1016/S1473-3099(11)70210-9. Epub 2011 Aug 16.
3
Questionable effectiveness of the QuantiFERON-TB Gold Test (Cellestis) as a screening tool in healthcare workers.QuantiFERON-TB Gold Test（Cellestis）作为医护人员筛查工具的有效性值得怀疑。
Infect Control Hosp Epidemiol. 2010 Dec;31(12):1279-85. doi: 10.1086/657336. Epub 2010 Oct 27.
4
Serial testing with the interferon-γ release assay in Portuguese healthcare workers.葡萄牙医护人员采用干扰素-γ释放试验进行系列检测。
Int Arch Occup Environ Health. 2011 Apr;84(4):461-9. doi: 10.1007/s00420-010-0571-x. Epub 2010 Aug 19.
5
Updated guidelines for using Interferon Gamma Release Assays to detect Mycobacterium tuberculosis infection - United States, 2010.更新的使用干扰素γ释放试验来检测结核分枝杆菌感染的指南-美国，2010 年。
MMWR Recomm Rep. 2010 Jun 25;59(RR-5):1-25.
6
Cost-effectiveness of interferon gamma release assays vs tuberculin skin tests in health care workers.医护人员中γ-干扰素释放试验与结核菌素皮肤试验的成本效益
Arch Intern Med. 2009 Jan 26;169(2):179-87. doi: 10.1001/archinternmed.2008.524.
7
Cost-effectiveness of a new interferon-based blood assay, QuantiFERON-TB Gold, in screening tuberculosis contacts.一种基于干扰素的新型血液检测——全血γ-干扰素释放试验（QuantiFERON-TB Gold）在筛查结核病接触者中的成本效益。
Int J Tuberc Lung Dis. 2008 Dec;12(12):1414-24.
8
Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update.系统评价：基于T细胞的检测方法用于潜伏性结核感染的诊断：最新进展
Ann Intern Med. 2008 Aug 5;149(3):177-84. doi: 10.7326/0003-4819-149-3-200808050-00241. Epub 2008 Jun 30.
9
Targeted tuberculin testing and treatment of latent tuberculosis infection. American Thoracic Society.潜伏性结核感染的靶向结核菌素检测与治疗。美国胸科学会。
MMWR Recomm Rep. 2000 Jun 9;49(RR-6):1-51.