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三名日光性视网膜病变患者的高清光谱域光学相干断层扫描结果及文献综述

High definition spectral domain optical coherence tomography findings in three patients with solar retinopathy and review of the literature.

作者信息

Chen Kevin C, Jung Jesse J, Aizman Alexander

机构信息

Department of Ophthalmology, New York University School of Medicine, New York, NY, USA.

出版信息

Open Ophthalmol J. 2012;6:29-35. doi: 10.2174/1874364101206010029. Epub 2012 Jun 15.

Abstract

PURPOSE

To describe ocular findings in 3 cases of solar retinopathy using high definition, spectral domain optical coherence tomography (SD-OCT) and review the literature for optical coherence tomography (OCT) characteristics associated with worse vision.

METHODS

Case series and retrospective review of clinical features and Spectralis SD-OCT (Heidelberg Engineering, Vista, California, United States of America). A literature review of OCT findings in cases of solar retinopathy reported on MEDLINE was also performed and analyzed.

RESULTS

Six eyes of 3 patients with solar retinopathy revealed significant foveal pathology. Visual acuity ranged from Snellen 20/30 to 20/50. High definition SD-OCT demonstrated defects at the level of the inner and outer segment junction of the photoreceptors as well as in the inner high reflective layer. There was a significant correlation between chronic disruption of the inner photoreceptor junction with worse vision based on the current case series and literature review.

CONCLUSIONS

Screening patients with exposure to central foveal damage from solar retinopathy with high definition SD-OCT improves diagnosis and assessment of photoreceptor damage and vision loss.

摘要

目的

使用高分辨率光谱域光学相干断层扫描(SD-OCT)描述3例日光性视网膜病变的眼部表现,并回顾与视力较差相关的光学相干断层扫描(OCT)特征的文献。

方法

病例系列研究及对临床特征和Spectralis SD-OCT(德国海德堡工程公司,美国加利福尼亚州维斯塔)进行回顾性分析。还对MEDLINE上报道的日光性视网膜病变病例的OCT检查结果进行了文献回顾和分析。

结果

3例日光性视网膜病变患者的6只眼中均发现明显的黄斑病变。视力范围为Snellen 20/30至20/50。高分辨率SD-OCT显示在光感受器内外节交界处以及内层高反射层存在缺损。基于当前的病例系列研究和文献回顾,内光感受器交界处的慢性破坏与较差的视力之间存在显著相关性。

结论

使用高分辨率SD-OCT对遭受日光性视网膜病变导致中央黄斑损伤的患者进行筛查,可改善对光感受器损伤和视力丧失的诊断及评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a45/3394112/feb51e9ff2f6/TOOPHTJ-6-29_F1.jpg

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