Northumbria Centre for Sleep Research, Northumbria University, Newcastle, UK.
J Psychiatr Res. 2012 Oct;46(10):1278-85. doi: 10.1016/j.jpsychires.2012.07.001. Epub 2012 Jul 15.
Despite Acute Insomnia being classified as a distinct nosological entity since 1979/1980 (ASDC/DSM III-R), there are no published estimates of its prevalence and incidence or data regarding transition to chronic insomnia or remission. This lack of data prevents an understanding of: a) the pathogenesis of insomnia and b) when and how treatment should be initiated. The aim of the present study was to provide such data from two community samples. Samples were recruited in the USA (n = 2861) and the North East of the UK (n = 1095). Additionally, 412 Normal Sleepers from the UK sample were surveyed longitudinally to determine prospectively incidence, transition, and remission rates for acute insomnia and assess whether the acute insomnia was a first episode, recurrent episode, or co-morbid with symptoms of other illnesses. The prevalence of acute insomnia was 9.5% (USA) and 7.9%(UK). The prevalence of three acute insomnia subtypes in the UK were; First-Onset Acute Insomnia 2.6%; Recurrent Acute Insomnia 3.8%; and 1.4% Co-morbid Acute Insomnia. The annual incidence of acute insomnia in the UK sample was between 31.2% and 36.6%. Remission rates fluctuated depending upon the definition of acute insomnia and whether the current episode was first-onset or recurrent. These findings provide preliminary insights into the natural history of insomnia. Such data will serve to inform how and when acute insomnia should be managed and whether such interventions may serve to diminish subsequent morbidity, particularly with respect to Major Depression.
尽管急性失眠自 1979/1980 年以来(ASDC/DSM III-R)已被归类为一种独特的疾病实体,但目前尚无关于其患病率和发病率的发表数据,也没有关于向慢性失眠或缓解过渡的数据。这些数据的缺乏阻碍了对以下方面的理解:a)失眠的发病机制和 b)何时以及如何开始治疗。本研究的目的是从两个社区样本中提供这些数据。样本在美国(n=2861)和英国东北部(n=1095)招募。此外,对英国样本中的 412 名正常睡眠者进行了纵向调查,以确定急性失眠的发生率、转变和缓解率,并评估急性失眠是首次发作、复发性发作还是与其他疾病的症状共病。急性失眠的患病率为 9.5%(美国)和 7.9%(英国)。英国三种急性失眠亚型的患病率分别为:首次发作性急性失眠 2.6%;复发性急性失眠 3.8%;以及 1.4%共病性急性失眠。英国样本中急性失眠的年发生率在 31.2%至 36.6%之间。缓解率取决于急性失眠的定义以及当前发作是首次发作还是复发性发作而波动。这些发现初步揭示了失眠的自然史。这些数据将有助于了解如何以及何时应管理急性失眠,以及此类干预措施是否可能减轻随后的发病率,特别是在与重度抑郁症相关的发病率方面。