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巴西圣保罗流行病学睡眠研究中失眠的客观患病率。

Objective prevalence of insomnia in the São Paulo, Brazil epidemiologic sleep study.

机构信息

Disciplina de Medicina e Biologia do Sono, Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil.

出版信息

Ann Neurol. 2013 Oct;74(4):537-46. doi: 10.1002/ana.23945. Epub 2013 Sep 16.

Abstract

OBJECTIVE

Using polysomnography, the gold standard for sleep assessment, this study aimed to describe the objective prevalence of insomnia in the São Paulo, Brazil, Epidemiologic Sleep Study cohort of 1,101 adults (20-80 years old).

METHODS

Objective insomnia was defined by meeting 1 of the following criteria: sleep onset latency >30 minutes (sleep initiating insomnia), wake after sleep onset lasting >30 minutes (sleep maintenance insomnia), total sleep time <360 minutes and a terminal wakefulness >30 minutes (insomnia with too short duration of sleep or early morning awakening), or a combination of the previous quantitative criteria (mixed disorder). Using validated questionnaires based on Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria, subjective insomnia was categorized into 3 groups: good sleepers, insomnia symptoms, and DSM-IV insomnia.

RESULTS

A total of 1,042 subjects participated in the study (95% response rate). The prevalence of objective insomnia was 32%. The subjective prevalence of insomnia symptoms was 45%, and the subjective prevalence of DSM-IV insomnia was 15%. Sociodemographic factors were similar in both the objective insomnia and the DSM-IV insomnia groups. Age, but not psychiatric symptoms, was predictive of objective insomnia. The subjective criteria were not adequately sensitive (36%) to identify objective insomnia, but were adequately specific (77%) to rule out polysomnography noninsomnia.

INTERPRETATION

The prevalence of objective insomnia assessed by polysomnography was higher than the prevalence of subjective insomnia according to DSM-IV-validated questionnaires. Clinical trials.gov ID: NCT00596713.

摘要

目的

本研究使用多导睡眠图(睡眠评估的金标准),旨在描述巴西圣保罗流行病学睡眠研究队列中 1101 名成年人(20-80 岁)的客观失眠患病率。

方法

客观失眠的定义为符合以下标准之一:入睡潜伏期>30 分钟(起始性失眠)、睡眠后觉醒持续>30 分钟(维持性失眠)、总睡眠时间<360 分钟和终端觉醒>30 分钟(睡眠持续时间过短或早醒性失眠),或之前定量标准的组合(混合性睡眠障碍)。使用基于精神障碍诊断与统计手册,第 4 版(DSM-IV)标准的经过验证的问卷,将主观失眠分为 3 组:睡眠良好者、失眠症状和 DSM-IV 失眠。

结果

共有 1042 名受试者参加了研究(95%的回复率)。客观失眠的患病率为 32%。失眠症状的主观患病率为 45%,DSM-IV 失眠的主观患病率为 15%。客观失眠组和 DSM-IV 失眠组的社会人口统计学因素相似。年龄,但不是精神症状,是客观失眠的预测因素。主观标准对识别客观失眠的敏感性(36%)不足,但特异性(77%)足以排除多导睡眠图非失眠。

解释

通过多导睡眠图评估的客观失眠患病率高于根据 DSM-IV 验证问卷评估的主观失眠患病率。临床试验.gov ID:NCT00596713。

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