Werewka-Maczuga Agnieszka, Osiński Tomasz, Chrzan Robert, Buczek Magda, Urbanik Andrzej
Radiology Department, Jagiellonian University Medical College, Cracow, Poland.
Pol J Radiol. 2011 Jul;76(3):38-48.
In this article, authors presented several characteristic features of Gastrointestinal Stromal Tumors (GISTs), which may lead to diagnostic errors and unexpected difficulties during interpretation of CT images. In case of GIST, one may encounter problems at every level of diagnostics and treatment response monitoring, especially after introduction of modern molecular targeting therapies. RECIST scale criteria, used until now for evaluation of response to treatment in solid tumors are based merely on the size of the tumor and turned out to be inadequate after introduction of treatment with new molecular target drugs such as Imatinib.
在本文中，作者介绍了胃肠道间质瘤（GIST）的几个特征，这些特征可能会在CT图像解读过程中导致诊断错误和意外困难。对于GIST，在诊断和治疗反应监测的各个层面都可能遇到问题，尤其是在引入现代分子靶向治疗之后。目前用于评估实体瘤治疗反应的RECIST标准仅仅基于肿瘤大小，在引入伊马替尼等新型分子靶向药物治疗后，该标准被证明是不够的。
