Sorial Verena, Khan Aramish S, Welsh Terry, Zhang Lei, Fayek Sameh A
Surgery, University of the Incarnate Word School of Osteopathic Medicine, San Antonio, USA.
Pathology, Parkview Community Hospital Medical Center, Riverside, USA.
Cureus. 2024 Apr 23;16(4):e58857. doi: 10.7759/cureus.58857. eCollection 2024 Apr.
Gastric schwannomas are an exceedingly rare tumor arising from the myenteric plexus of the gastrointestinal enteric nervous system. These schwannomas are most commonly benign and reported to occur in female patients with a mean age of 58 at presentation. They are most often discovered incidentally, but can occasionally present with abdominal discomfort, obstructive symptoms, or GI bleeding. Frequently, the initial clinical consideration is for a gastrointestinal stromal tumor, which is much more common. A definitive diagnosis is made with microscopic imaging and immunohistochemical staining. Complete surgical resection, typically performed laparoscopically, is the most definitive and usually curative treatment, requiring no further follow-up. Herein, we present the first and only case of gastric schwannoma in an octogenarian and discuss an update on current diagnostic and therapeutic options.
胃神经鞘瘤是一种极为罕见的肿瘤，起源于胃肠神经系统的肌间神经丛。这些神经鞘瘤大多为良性，据报道好发于女性患者，平均发病年龄为58岁。它们最常为偶然发现，但偶尔也会出现腹部不适、梗阻症状或胃肠道出血。通常，最初的临床考虑是胃肠道间质瘤，后者更为常见。通过显微镜成像和免疫组化染色可做出明确诊断。完整的手术切除通常通过腹腔镜进行，是最确切且通常可治愈的治疗方法，无需进一步随访。在此，我们报告了首例也是唯一一例发生于八旬老人的胃神经鞘瘤病例，并讨论了当前诊断和治疗选择的最新情况。
