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高效抗逆转录病毒治疗（HAART）相关的急性微生物学阴性缺氧性间质性肺炎：免疫重建炎症综合征掩盖了具有非典型表现的耶氏肺孢子菌感染。

Acute microbiologically negative hypoxic interstitial pneumonia on HAART: Immune Reconstitution Inflammatory Syndrome unmasking Pneumocystis jiroveci infection with an atypical presentation.

作者信息

Sovaila S, de Raigniac A, Picard C, Taulera O, Lascoux-Combe C, Sereni D, Bourgarit A

机构信息

Department of Internal Medicine, Saint-Louis Hospital, AP-HP, Paris, France.

出版信息

J Med Life. 2012 Jun 12;5(2):189-91. Epub 2012 Jun 18.

PMID:22802889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3391890/
Abstract

Highly active antiretroviral therapy for AIDS sometimes engenders inflammatory manifestations resulting from an inappropriate and unbalanced immune-system restoration, called Immune Reconstitution inflammatory Syndrome, which, in turn, can unmask a subclinical infection/pathology. Despite our patient's evident syndrome, the atypical clinical, microbiologic and radiologic feature of Pneumocystis pneumonia made its diagnosis difficult.

摘要

用于治疗艾滋病的高效抗逆转录病毒疗法有时会引发因免疫系统恢复不当和失衡而导致的炎症表现，即免疫重建炎症综合征，进而可能使亚临床感染/病理显现出来。尽管我们的患者有明显的综合征，但肺孢子菌肺炎的非典型临床、微生物学和放射学特征使其诊断困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c9b/3391890/614c5535ae4c/JMedLife-05-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c9b/3391890/614c5535ae4c/JMedLife-05-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c9b/3391890/614c5535ae4c/JMedLife-05-189-g001.jpg

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JAMA. 2009 Jun 24;301(24):2578-85. doi: 10.1001/jama.2009.880.
2
[53 year-old patient with fever and cough].[53岁发热伴咳嗽患者]
Internist (Berl). 2009 Jul;50(7):877-80. doi: 10.1007/s00108-009-2340-z.
3
Immune reconstitution inflammatory syndrome after initiating highly active antiretroviral therapy in HIV-infected children.HIV感染儿童开始高效抗逆转录病毒治疗后出现的免疫重建炎症综合征
Pediatr Radiol. 2009 Jun;39(6):569-74. doi: 10.1007/s00247-009-1192-y. Epub 2009 Mar 10.
4
Biomarkers of HIV Immune Reconstitution Inflammatory Syndrome.HIV免疫重建炎症综合征的生物标志物
Biomark Med. 2008;2(4):349-361. doi: 10.2217/17520363.2.4.349.
5
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Braz J Infect Dis. 2007 Dec;11(6):549-53. doi: 10.1590/s1413-86702007000600005.
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Thoracic manifestations of immune restoration syndromes in AIDS.艾滋病免疫重建综合征的胸部表现
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