Departamento de Psicobiologia-Campus São Paulo, Universidade Federal de São Paulo, São Paulo, Brasil.
Psychophysiology. 2012 Sep;49(9):1298-306. doi: 10.1111/j.1469-8986.2012.01411.x. Epub 2012 Jul 16.
This work evaluated the importance of sleep on mood and cognition after 24 h of exposure to hypoxia. Ten males, aged 23-30 years, were placed in a normobaric chamber simulating an altitude of 4,500 m. Sleep assessments were conducted from 22:00-6:00; all mood and cognitive assessments were performed 20 min after awakening. The assessments were conducted in normoxic conditions and after 24 h of hypoxia. Sleep was reevaluated 14 h after the start of exposure to hypoxic conditions, and mood state and cognitive functions were reevaluated 24 h after the start of exposure to hypoxic conditions. Hypoxia reduced total sleep time, sleep efficiency, slow-wave sleep, and rapid eye movement. Depressive mood, anger, and fatigue increased under hypoxic conditions. Vigor, attention, visual and working memory, concentration, executive functions, inhibitory control, and speed of mental processing worsened. Changes in sleep patterns can modulate mood and cognition after 24 h.
这项工作评估了在暴露于缺氧 24 小时后睡眠对情绪和认知的重要性。10 名年龄在 23 至 30 岁之间的男性被安置在模拟海拔 4500 米的常压舱中。睡眠评估从 22:00 进行到 6:00；所有情绪和认知评估都是在唤醒后 20 分钟进行的。评估在正常氧合条件下和暴露于缺氧 24 小时后进行。在开始暴露于缺氧条件后 14 小时重新评估睡眠，在开始暴露于缺氧条件后 24 小时重新评估情绪状态和认知功能。缺氧会减少总睡眠时间、睡眠效率、慢波睡眠和快速眼动。在缺氧条件下，抑郁情绪、愤怒和疲劳感会增加。活力、注意力、视觉和工作记忆、注意力、执行功能、抑制控制和心理处理速度都会恶化。睡眠模式的变化可能会在 24 小时后调节情绪和认知。
