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肾同种移植及硫唑嘌呤和泼尼松治疗后发生的网状细胞肉瘤

Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy.

作者信息

Doak P B, Montgomerie J Z, North J D, Smith F

出版信息

Br Med J. 1968 Dec 21;4(5633):746-8. doi: 10.1136/bmj.4.5633.746.

DOI:10.1136/bmj.4.5633.746
PMID:4881420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1912885/
Abstract

Two patients developed reticulum cell sarcomata after they had been treated with azathioprine and prednisone in the course of cadaveric renal transplantation. Both had terminal widespread herpes simplex virus infection.Immunosuppressive therapy could be responsible for an increased risk of malignant lymphomata either directly or by facilitating infection with oncogenic viruses.

摘要

两名患者在尸体肾移植过程中接受硫唑嘌呤和泼尼松治疗后发生了网状细胞肉瘤。两人均患有终末期广泛的单纯疱疹病毒感染。免疫抑制治疗可能直接或通过促进致癌病毒感染导致恶性淋巴瘤风险增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/f0b37c054aa4/brmedj02115-0045-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/945c5094db46/brmedj02115-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/d584c69a9ac4/brmedj02115-0045-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/f0b37c054aa4/brmedj02115-0045-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/945c5094db46/brmedj02115-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/d584c69a9ac4/brmedj02115-0045-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbab/1912885/f0b37c054aa4/brmedj02115-0045-c.jpg

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1
Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy.肾同种移植及硫唑嘌呤和泼尼松治疗后发生的网状细胞肉瘤
Br Med J. 1968 Dec 21;4(5633):746-8. doi: 10.1136/bmj.4.5633.746.
2
Cerebral reticulum cell sarcoma after multiple renal transplants.多次肾移植后发生的脑网状细胞肉瘤。
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Primary reticulum cell sarcoma of the brain in a renal transplantation recipient.一名肾移植受者发生的原发性脑网状细胞肉瘤。
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[Malignant T-cell neoplasia during treatment with azathioprine and prednisone after kidney transplantation].肾移植后硫唑嘌呤和泼尼松治疗期间的恶性T细胞肿瘤形成
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Arch Esp Urol. 1990 Mar;43(2):155-8.

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本文引用的文献

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CADAVERIC RENAL HOMOTRANSPLANTATION WITH INADVERTENT TRANSPLANTATION OF CARCINOMA.尸体肾同种移植伴癌的意外移植
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Immune reactivity prior to development of thymic lymphoma in C57BL mice.C57BL小鼠胸腺淋巴瘤发生前的免疫反应性。
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病例报告:肺移植受者中不可忽视的 EBV 相关移植后淋巴组织增生性疾病。
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EBV+ lymphoproliferative diseases: opportunities for leveraging EBV as a therapeutic target.EBV+ 淋巴增殖性疾病:利用 EBV 作为治疗靶点的机会。
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Malignant lymphoma of the cervix in a bicollis uterus considered to be a post-transplant lymphoproliferative disorder in a patient after renal transplantation: A case report.双子宫宫颈恶性淋巴瘤,考虑为肾移植术后患者的移植后淋巴细胞增生性疾病:一例报告。
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Post Transplant Lymphoproliferative Disorder.移植后淋巴细胞增殖性疾病
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Multicentric Castleman's disease in a renal allograft recipient: a case report and literature review.肾移植受者的多中心Castleman病:一例报告及文献复习
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Post-transplant lymphoproliferative disorder presenting with multifocal aggressive osseous lesions.移植后淋巴细胞增生性疾病伴多灶性侵袭性骨病变。
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Colorectal Cancer Characteristics and Outcomes after Solid Organ Transplantation.实体器官移植后的结直肠癌特征与结局
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Malignant lymphomas following allogenic disease: transition from an immunological to a neoplastic disorder.同种异体疾病后的恶性淋巴瘤:从免疫性疾病向肿瘤性疾病的转变。
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Antilymphocytic serum and tumour dissemination.抗淋巴细胞血清与肿瘤播散
Br Med J. 1968 Jun 1;2(5604):533-5. doi: 10.1136/bmj.2.5604.533.
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6-mercaptopurine administration to NZB mice.给新西兰黑小鼠施用6-巯基嘌呤。
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Immunologic rejection of human cancer transplanted with a renal allograft.
N Engl J Med. 1968 Feb 29;278(9):479-83. doi: 10.1056/NEJM196802292780904.
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Malignant lymphoproliferative diseases: interactions between immunological abnormalities and oncogenic viruses.恶性淋巴增殖性疾病:免疫异常与致癌病毒之间的相互作用。
Annu Rev Med. 1968;19:269-82. doi: 10.1146/annurev.me.19.020168.001413.
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Effects of antilymphocyte serum on virus oncogenesis.抗淋巴细胞血清对病毒致癌作用的影响。
Proc Soc Exp Biol Med. 1968 Jan;127(1):207-12. doi: 10.3181/00379727-127-32657.
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Agent of Marek's disease in tissue culture.马立克氏病病毒在组织培养中的作用因子。
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