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经腹膜后柔性内镜清创术治疗感染性胰腺坏死的管理:10 年经验。

Management of infected pancreatic necrosis using retroperitoneal necrosectomy with flexible endoscope: 10 years of experience.

机构信息

Department of General Surgery, Virgen de la Arrixaca University Hospital, 30120 Murcia, Spain.

出版信息

Surg Endosc. 2013 Feb;27(2):443-53. doi: 10.1007/s00464-012-2455-5. Epub 2012 Jul 18.

Abstract

BACKGROUND

This study was designed to provide our experience in the management of infected and drained pancreatic necrosis using the retroperitoneal approach.

METHODS

This was a prospective observational study in a tertiary care university hospital. Thirty-two patients with confirmed infected pancreatic necrosis were studied. Superficial necrosectomy was performed with lavage and aspiration of debris. This was achieved though a retroperitoneal approach of the pancreatic area and under the direct vision of a flexible endoscope. The follow-up procedure using retroperitoneal endoscopy did not require taking the patient to the operating room. The main outcome measures were infection control, morbidity, and mortality related to technique, reintervention, and long-term follow-up.

RESULTS

No significant morbidity or mortality related to the technique was observed in all of the patients with infected pancreatic necrosis treated with this retroperitoneal approach compared with published data using other approaches. Reinterventions were not required and patients are currently asymptomatic.

CONCLUSIONS

Retroperitoneal access of the pancreatic area is a good approach for drainage and debridement of infected pancreatic necrosis. Translumbar retroperitoneal endoscopy allows exploration under direct visual guidance avoiding open transabdominal reintervention and the risk of contamination of the abdominal cavity. This technique does not increase morbidity and mortality, can be performed at the patients' bedside as many times as necessary, and has advantages over other retroperitoneal approaches.

摘要

背景

本研究旨在提供我们使用腹膜后入路处理感染性胰腺坏死的经验。

方法

这是一项在三级护理大学医院进行的前瞻性观察性研究。研究了 32 例确诊为感染性胰腺坏死的患者。通过腹膜后胰腺区域的入路,在柔性内窥镜的直接视野下进行浅表性坏死组织切除术,并进行冲洗和抽吸。后续的腹膜后内窥镜检查程序无需将患者送往手术室。主要观察指标为与技术、再次干预和长期随访相关的感染控制、发病率和死亡率。

结果

与使用其他方法的已发表数据相比,所有接受腹膜后入路治疗的感染性胰腺坏死患者均未观察到与该技术相关的明显发病率或死亡率。无需再次干预,患者目前无症状。

结论

腹膜后入路是治疗感染性胰腺坏死的一种良好方法,可进行引流和清创。经腰椎腹膜后内镜检查可在直视下进行探查,避免了开腹再次干预和腹腔污染的风险。该技术不会增加发病率和死亡率,可根据需要在患者床边多次进行,并且优于其他腹膜后入路。

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