Duckett Jonathan, Cheema Katherine, Patil Avanti, Basu Maya, Beale Sian, Wise Brian
Department of Obstetrics and Gynaecology, Medway NHS Foundation Trust, Windmill Road, Gillingham, Kent ME7 5NY, UK.
Int Urogynecol J. 2013 Mar;24(3):447-52. doi: 10.1007/s00192-012-1883-z. Epub 2012 Jul 20.
The relationship between free flow (FFS) and pressure flow (PFS) voiding studies remains uncertain and the effect of a urethral catheter on flow rates has not been determined. The relationship between residuals obtained at FF and PFS has yet to be established.
This was a prospective cohort study based on 474 consecutive women undergoing cystometry using different sized urethral catheters at different centres. FFS and PFS data were compared for different conditions and the relationship of residuals analysed for FFS and PFS. The null hypothesis was that urethral catheters do not produce an alteration in maximum flow rates for PFS and FF studies.
Urethral catheterisation results in lower flow rates (p < 0.01) and this finding is confirmed when flows are corrected for voided volume (p < 0.01). FFS and PFS maximum flow rates are lower in women with DO than USI (p < 0.01). A 6-F urethral catheter does not have a significantly greater effect than a 4.5-F urethral catheter. A mathematical model can be applied to transform FFS to PFS flow rates and vice versa. There was no significant difference between the mean residuals of the two groups (FFS vs PFS-two-tailed t = 0.54, p = 0.59). Positive residuals in FFS showed a good association with positive residuals in the PFS (r = 0.53, p < 0.01)
Urethral catheterisation results in lower maximum flow rates. The relationship can be compared mathematically. The null hypothesis can be rejected.
自由流（FFS）排尿研究与压力流（PFS）排尿研究之间的关系仍不明确，且尿道导管对流速的影响尚未确定。FFS和PFS时测得的残余尿量之间的关系也尚未确立。
这是一项前瞻性队列研究，基于474名在不同中心使用不同尺寸尿道导管进行膀胱测压的连续女性。比较了不同条件下的FFS和PFS数据，并分析了FFS和PFS时残余尿量的关系。原假设是尿道导管不会使PFS和FFS研究中的最大流速发生改变。
尿道插管导致流速降低（p < 0.01），当对尿量进行校正后，这一发现得到证实（p < 0.01）。逼尿肌过度活动（DO）女性的FFS和PFS最大流速低于逼尿肌不稳定（USI）女性（p < 0.01）。6-F尿道导管的影响并不显著大于4.5-F尿道导管。可以应用数学模型将FFS流速转换为PFS流速，反之亦然。两组的平均残余尿量之间无显著差异（FFS与PFS——双侧t = 0.54，p = 0.59）。FFS中的正残余尿量与PFS中的正残余尿量显示出良好的相关性（r = 0.53，p < 0.01）
尿道插管导致最大流速降低。这种关系可以通过数学方法进行比较。原假设可以被拒绝。
