急性和受损的伤口愈合：病理生理学和当前的药物输送方法，第 2 部分：生长因子在正常和病理性伤口愈合中的作用：治疗潜力和输送方法。
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery.
机构信息
Tufts University School of Medicine, Boston, Massachusetts, USA.
出版信息
Adv Skin Wound Care. 2012 Aug;25(8):349-70. doi: 10.1097/01.ASW.0000418541.31366.a3.
Abstract
This is the second of 2 articles that discuss the biology and pathophysiology of wound healing, reviewing the role that growth factors play in this process and describing the current methods for growth factor delivery into the wound bed.
摘要
这是讨论伤口愈合的生物学和病理生理学的 2 篇文章中的第 2 篇，回顾了生长因子在这一过程中所起的作用，并描述了目前将生长因子递送到创床的方法。
相似文献
1
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery.急性和受损的伤口愈合：病理生理学和当前的药物输送方法，第 2 部分：生长因子在正常和病理性伤口愈合中的作用：治疗潜力和输送方法。
Adv Skin Wound Care. 2012 Aug;25(8):349-70. doi: 10.1097/01.ASW.0000418541.31366.a3.
2
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care.急性和受损的伤口愈合：病理生理学和当前的药物输送方法，第 1 部分：正常和慢性伤口：生物学、原因和护理方法。
Adv Skin Wound Care. 2012 Jul;25(7):304-14. doi: 10.1097/01.ASW.0000416006.55218.d0.
3
Current thoughts on angiogenesis.关于血管生成的当前观点。
J Wound Care. 2009 Jan;18(1):12-4, 16. doi: 10.12968/jowc.2009.18.1.32134.
4
Innovative approaches in wound healing: trajectory and advances.创新的伤口愈合方法：轨迹与进展。
Artif Cells Nanomed Biotechnol. 2013 Jun;41(3):202-12. doi: 10.3109/21691401.2012.716065. Epub 2013 Jan 15.
5
Specific growth factors and the healing of chronic wounds.特定生长因子与慢性伤口愈合
J Wound Care. 2001 May;10(5):173-8. doi: 10.12968/jowc.2001.10.5.26076.
6
Growth factors: the wound healing therapy of the future.生长因子：未来的伤口愈合疗法。
Br J Community Nurs. 2003 Sep;8(9):S15-6, S18-9, S22-3. doi: 10.12968/bjcn.2003.8.Sup4.11585.
7
Growth factors in the treatment of diabetic foot ulcers.生长因子在糖尿病足溃疡治疗中的应用
Br J Surg. 2003 Feb;90(2):133-46. doi: 10.1002/bjs.4019.
8
Wound healing: the role of growth factors.伤口愈合：生长因子的作用
Drugs Today (Barc). 2003 Oct;39(10):787-800. doi: 10.1358/dot.2003.39.10.799472.
9
Growth factors in wound healing: the present and the future?伤口愈合中的生长因子：现状与未来？
Clin Podiatr Med Surg. 2015 Jan;32(1):109-19. doi: 10.1016/j.cpm.2014.09.010.
10
[Advances in the research of delivery system of growth factor and the gene for promoting wound healing].生长因子及促进伤口愈合基因递送系统的研究进展
Zhonghua Shao Shang Za Zhi. 2018 Aug 20;34(8):566-569. doi: 10.3760/cma.j.issn.1009-2587.2018.08.018.
引用本文的文献
1
Synergistic effects of mesenchymal stem cells and their secretomes with scaffolds in burn wound healing: a systematic review and meta-analysis of preclinical studies.间充质干细胞及其分泌产物与支架在烧伤创面愈合中的协同作用：一项临床前研究的系统评价和荟萃分析
J Transl Med. 2025 Jul 1;23(1):708. doi: 10.1186/s12967-025-06712-y.
2
Marine Jellyfish Collagen and Other Bioactive Natural Compounds from the Sea, with Significant Potential for Wound Healing and Repair Materials.海洋水母胶原蛋白及其他来自海洋的生物活性天然化合物，在伤口愈合和修复材料方面具有巨大潜力。
Mar Drugs. 2025 Jun 13;23(6):252. doi: 10.3390/md23060252.
3
From Growth Factors to Structure: PDGF and TGF-β in Granulation Tissue Formation. A Literature Review.从生长因子到结构：血小板衍生生长因子和转化生长因子-β在肉芽组织形成中的作用。文献综述
J Cell Mol Med. 2025 Jun;29(11):e70374. doi: 10.1111/jcmm.70374.
4
Efficacy of Topical Oil for Oral Wound Healing in Rats.局部用油对大鼠口腔伤口愈合的疗效
Laryngoscope Investig Otolaryngol. 2025 Jun 4;10(3):e70153. doi: 10.1002/lio2.70153. eCollection 2025 Jun.
5
Insights into Liposomal and Gel-Based Formulations for Dermatological Treatments.皮肤治疗用脂质体和凝胶制剂的见解
Gels. 2025 Mar 26;11(4):245. doi: 10.3390/gels11040245.
6
Multifunctional metal-organic frameworks as promising nanomaterials for antimicrobial strategies.多功能金属有机框架作为用于抗菌策略的有前景的纳米材料。
Burns Trauma. 2025 Jan 24;13:tkaf008. doi: 10.1093/burnst/tkaf008. eCollection 2025.
7
Application of Gelatin/Vanillin/Fe/AGP-AgNPs Hydrogels Promotes Wound Contraction, Enhances Dermal Growth Factor Expression, and Minimizes Skin Irritation.明胶/香兰素/铁/AGP-银纳米粒子水凝胶的应用促进伤口收缩，增强真皮生长因子表达，并使皮肤刺激最小化。
ACS Omega. 2025 Mar 4;10(10):10530-10545. doi: 10.1021/acsomega.4c10648. eCollection 2025 Mar 18.
8
The Role of Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles in Modulating Dermal Fibroblast Activity: A Pathway to Enhanced Tissue Regeneration.脐带间充质干细胞衍生的细胞外囊泡在调节真皮成纤维细胞活性中的作用：增强组织再生的途径
Biology (Basel). 2025 Feb 1;14(2):150. doi: 10.3390/biology14020150.
9
Regenerative effect of lyophilized dental follicle mesenchymal stem cells and platelet-rich fibrin in skin wounds in geriatric and young rats.冻干牙囊间充质干细胞和富血小板纤维蛋白对老年和年轻大鼠皮肤伤口的再生作用
Sci Rep. 2025 Feb 24;15(1):6623. doi: 10.1038/s41598-025-85238-1.
10
Causal relationship between circulating inflammatory cytokines and the risk of hernia: a bidirectional Mendelian randomization study.循环炎症细胞因子与疝气风险之间的因果关系：一项双向孟德尔随机化研究
J Int Med Res. 2025 Feb;53(2):3000605251315923. doi: 10.1177/03000605251315923.
本文引用的文献
1
Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects.壳聚糖制剂在创伤和烧伤中的应用：抗菌和促进伤口愈合的作用。
Expert Rev Anti Infect Ther. 2011 Jul;9(7):857-79. doi: 10.1586/eri.11.59.
2
Bioactive peptides derived from vascular endothelial cell extracellular matrices promote microvascular morphogenesis and wound healing in vitro.血管内皮细胞细胞外基质衍生的生物活性肽促进体外微血管形态发生和伤口愈合。
Wound Repair Regen. 2011 Jan-Feb;19(1):59-70. doi: 10.1111/j.1524-475X.2010.00642.x. Epub 2010 Dec 6.
3
Advances in viral-vector systemic cytokine gene therapy against cancer.病毒载体系统细胞因子基因治疗癌症的进展。
Vaccine. 2010 May 21;28(23):3883-7. doi: 10.1016/j.vaccine.2010.03.041. Epub 2010 Apr 4.
4
Fibroblast growth factor signalling: from development to cancer.成纤维细胞生长因子信号通路：从发育到癌症。
Nat Rev Cancer. 2010 Feb;10(2):116-29. doi: 10.1038/nrc2780.
5
Formulations and delivery vehicles for bone morphogenetic proteins: latest advances and future directions.骨形态发生蛋白的制剂和传递载体：最新进展和未来方向。
Injury. 2009 Dec;40 Suppl 3:S8-11. doi: 10.1016/S0020-1383(09)70004-X.
6
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.经载体给药 1.5 年后，莱伯先天性黑蒙的基因治疗是安全有效的。
Mol Ther. 2010 Mar;18(3):643-50. doi: 10.1038/mt.2009.277. Epub 2009 Dec 1.
7
Angiogenesis, vascular endothelial growth factor and its receptors in human surgical wounds.人体手术伤口中的血管生成、血管内皮生长因子及其受体
Br J Surg. 2009 Dec;96(12):1484-91. doi: 10.1002/bjs.6778.
8
Fibrin sealant: past, present, and future: a brief review.纤维蛋白胶：过去、现在和未来：简要回顾。
World J Surg. 2010 Apr;34(4):632-4. doi: 10.1007/s00268-009-0252-7.
9
Fibrin sealant combined with fibroblasts and platelet-derived growth factor enhance wound healing in excisional wounds.纤维蛋白密封剂联合成纤维细胞和血小板衍生生长因子可促进切除伤口的愈合。
Wound Repair Regen. 2009 May-Jun;17(3):405-10. doi: 10.1111/j.1524-475X.2009.00481.x.
10
The biological effects of topical alginate treatment in an animal model of skin wound healing.局部藻酸盐治疗在皮肤伤口愈合动物模型中的生物学效应。
Wound Repair Regen. 2009 Jul-Aug;17(4):505-10. doi: 10.1111/j.1524-475X.2009.00496.x. Epub 2009 Jun 10.
Zotero 插件