Department of Psychiatry and Behavioural Neurosciences, McMaster University, Ontario, Canada.
Int J Eat Disord. 2013 Jan;46(1):3-11. doi: 10.1002/eat.22042. Epub 2012 Jul 23.
To systematically review and quantitatively evaluate the efficacy of Family-Based Treatment (FBT) compared with individual treatment among adolescents with eating disorders.
The literature was reviewed using the MEDLINE search terms "family therapy AND Anorexia Nervosa," and "family therapy AND Bulimia Nervosa". This produced 12 randomized controlled trials involving adolescents with eating disorders and family therapy which were reviewed carefully for several inclusion criteria including: allocation concealment, intent-to-treat analysis, assessor blinding, behavioral family therapy compared with an individual therapy, and adolescent age group. References from these articles were searched. Only three studies met these strict inclusion criteria for meta-analysis. A random effects model and odds ratio was used for meta-analysis, looking at "remission" as the outcome of choice.
When combined in a meta-analysis, end of treatment data indicated that FBT was not significantly different from individual treatment (z = 1.62, p = 0.11). However, when follow-up data from 6 to 12 months were analyzed, FBT was superior to individual treatment (z = 2.94, p < 0.003), and heterogeneity was not significant (p = 0.59).
Although FBT does not appear to be superior to individual treatment at end of treatment, there appear to be significant benefits at 6-12 month follow-up for adolescents suffering from eating disorders.
系统回顾和定量评估家庭为基础的治疗（FBT）与个体治疗在青少年饮食障碍中的疗效。
使用 MEDLINE 搜索词“家庭治疗和神经性厌食症”和“家庭治疗和神经性贪食症”对文献进行综述。这产生了 12 项涉及饮食障碍青少年和家庭治疗的随机对照试验，仔细审查了几个纳入标准，包括：分配隐匿、意向治疗分析、评估者盲法、行为家庭治疗与个体治疗比较，以及青少年年龄组。还搜索了这些文章的参考文献。只有三项研究符合严格的纳入标准进行荟萃分析。使用随机效应模型和优势比进行荟萃分析，选择“缓解”作为选择的结果。
当组合在荟萃分析中时，治疗结束时的数据表明 FBT 与个体治疗没有显著差异（z = 1.62，p = 0.11）。然而，当分析 6 至 12 个月的随访数据时，FBT 优于个体治疗（z = 2.94，p < 0.003），且异质性不显著（p = 0.59）。
尽管 FBT 在治疗结束时似乎并不优于个体治疗，但对于患有饮食障碍的青少年，在 6-12 个月的随访中似乎有显著的益处。
