Hambleton Ashlea, Le Grange Daniel, Touyz Stephen, Maguire Sarah
InsideOut Institute, University of Sydney, Sydney Local Health District, Sydney, NSW 2000, Australia.
UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94107, USA.
Nutrients. 2025 Jun 28;17(13):2160. doi: 10.3390/nu17132160.
Anorexia Nervosa (AN) is a psychiatric illness with serious medical and physiological implications. Anorexia Nervosa is characterised by significant disruptions in weight, growth and physical health resulting from disordered behaviours such as food restriction, purging and inappropriate exercise. The illness is associated with substantial physical, psychological, social and economic burdens affecting all areas of functioning. Typically emerging in adolescence, AN can have a chronic course and high risk of mortality, with evidence suggesting that approximately 10% of individuals diagnosed with AN will die from medical complications or completed suicide. Whilst inpatient treatment reduces mortality risks through nutritional and weight restoration, outpatient treatment is the preferred level of intervention. In the case of adolescents, family-based treatment (FBT) is the recommended and most researched outpatient model for medically stable adolescents. However, access to FBT is limited, and there are several barriers that exist to receiving care from trained clinicians. This review provides a literature update on studies reporting the real-world access challenges for FBT, with particular attention paid to non-research settings. The review also highlights how digitally delivered treatment, specifically telehealth, has been used to increase access to FBT and examines the preliminary outcomes of telehealth-delivered FBT, which appear comparable to traditional in-person care. Despite these promising findings, provider, intervention and systemic factors have challenged the delivery of traditional in-person and telehealth FBT in real-world settings. Critical areas for future research include the need to understand the impact of potential confounders and what adaptions may be required to increase model feasibility in community settings, where access to specialist services is often limited and access challenges are most felt.
神经性厌食症(AN)是一种具有严重医学和生理影响的精神疾病。神经性厌食症的特征是由于食物限制、催吐和不适当运动等紊乱行为导致体重、生长和身体健康出现显著紊乱。该疾病伴随着影响所有功能领域的重大身体、心理、社会和经济负担。AN通常在青春期出现,可能病程慢性且死亡率高,有证据表明,约10%被诊断为AN的个体将死于医学并发症或自杀。虽然住院治疗通过营养和体重恢复降低了死亡风险,但门诊治疗是首选的干预级别。对于青少年而言,基于家庭的治疗(FBT)是针对病情稳定的青少年推荐且研究最多的门诊治疗模式。然而,获得FBT的机会有限,接受训练有素的临床医生治疗存在诸多障碍。本综述提供了有关报告FBT在现实世界中获取挑战的研究的文献更新,特别关注非研究环境。该综述还强调了数字交付治疗,特别是远程医疗,如何被用于增加获得FBT的机会,并研究了远程医疗提供的FBT的初步结果,这些结果似乎与传统的面对面护理相当。尽管有这些令人鼓舞的发现,但提供者、干预措施和系统因素在现实世界环境中对传统的面对面和远程医疗FBT的提供构成了挑战。未来研究的关键领域包括需要了解潜在混杂因素的影响,以及可能需要哪些调整来提高该模式在社区环境中的可行性,在社区环境中,获得专科服务的机会往往有限,获取挑战最为突出。