College of Pharmacy, Federal University of Sergipe, Brazil.
J Am Pharm Assoc (2003). 2012 Jul-Aug;52(4):515-8, 1 p following 518. doi: 10.1331/JAPhA.2012.11015.
To evaluate the effect of a pilot pharmaceutical care program developed for elderly patients with uncontrolled hypertension.
Nonrandomized single intervention pre/posttest blood pressure study in a community pharmacy in Aracaju, Brazil. This study enrolled elderly patients diagnosed with essential hypertension and uncontrolled blood pressure. Monthly visits were scheduled during a 10-month period. Pharmaceutical interventions were focused on health education and monitoring of drug-related problems. Primary outcomes included target blood pressure control, reduction in blood pressure, pulse pressure, medication adherence, and reduction of anthropometric indices.
35 of 51 patients completed the study. After 10 months of intervention, 57.2% of elderly patients achieved blood pressure control (P = 0.000) and the mean reduction was 26.6 mm Hg (P < 0.0001) for systolic blood pressure, 10.4 mm Hg (P < 0.0001) for diastolic blood pressure, and 15.7 mm Hg (P < 0.0001) for pulse pressure. Medication adherence also improved (P = 0.0000); however, anthropometric indices remained unchanged.
The pharmaceutical care program improved outcomes by reducing and controlling blood pressure and improving medication adherence among elderly patients with uncontrolled hypertension.
评估为控制不佳的老年高血压患者制定的试点药物治疗计划的效果。
在巴西阿拉卡茹的一家社区药房进行的非随机单干预前后血压研究。本研究纳入了诊断为原发性高血压且血压控制不佳的老年患者。在 10 个月的时间里安排每月一次的就诊。药物干预侧重于健康教育和监测与药物相关的问题。主要结局包括目标血压控制、血压降低、脉压降低、药物依从性和体重指数降低。
51 名患者中有 35 名完成了研究。干预 10 个月后，57.2%的老年患者血压得到控制（P = 0.000），收缩压平均降低 26.6mmHg（P < 0.0001），舒张压降低 10.4mmHg（P < 0.0001），脉压降低 15.7mmHg（P < 0.0001）。药物依从性也有所改善（P = 0.0000）；然而，体重指数没有变化。
药物治疗计划通过降低和控制血压以及改善老年高血压患者的药物依从性来改善结局。
