人类低渗肿胀试验、精液评分与去透明带仓鼠卵穿透试验的相关性

Correlation of the hypo-osmotic swelling test, semen score and the zona-free hamster egg penetration assay in humans.

作者信息

Okada A, Inomata K, Matsuhashi M, Fujio K, Miura K, Shiina K, Shirai M

机构信息

2nd Department of Anatomy, School of Medicine, Toho University, Tokyo, Japan.

出版信息

Int J Androl. 1990 Oct;13(5):337-43. doi: 10.1111/j.1365-2605.1990.tb01041.x.

DOI:10.1111/j.1365-2605.1990.tb01041.x

PMID:2283179

Abstract

The correlation between the hypo-osmotic swelling test, the modified Eliasson score for human semen analysis and the hamster egg penetration assay was examined. The results showed a weak but significant correlation between the group of subjects with swelling rates below 50% and the above 80% group. These groups showed hamster egg penetration assay rates of 9 +/- 14% and 39 +/- 29%, respectively (P less than 0.035). A significant correlation was also found between modified Eliasson scores (17 +/- 10 and 5 +/- 7, respectively) and swelling rates below 50% and above 70% (P less than 0.001). These results suggest that spermatozoa showing a low swelling rate have a poor fertilizing capacity. Therefore, the swelling tests and analysis of the patients semen can be used to discriminate sperm quality.

摘要

研究了低渗肿胀试验、人类精液分析的改良艾利亚松评分与仓鼠卵穿透试验之间的相关性。结果显示，肿胀率低于50%的受试者组与高于80%的受试者组之间存在微弱但显著的相关性。这些组的仓鼠卵穿透试验率分别为9±14%和39±29%（P<0.035）。在改良艾利亚松评分（分别为17±10和5±7）与低于50%和高于70%的肿胀率之间也发现了显著相关性（P<0.001）。这些结果表明，肿胀率低的精子受精能力差。因此，肿胀试验和患者精液分析可用于鉴别精子质量。