Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital Boston, Boston, Massachusetts 02115, USA.
J Pain. 2012 Sep;13(9):827-35. doi: 10.1016/j.jpain.2012.05.002. Epub 2012 Jul 24.
The current study examined the Fear Avoidance (FA) model of chronic pain in pediatric chronic pain patients. Multiple structural equation models were tested in the current study with pairwise parameter comparisons made between younger children (8-12 years) and adolescents (13-17 years). Within a sample of 350 children and adolescents, we examined functional disability and depressive symptoms in separate models with the following predictor variables-pain, pain catastrophizing, fear of pain, and avoidance of activities-after controlling for duration of pain. For a subset of patients (n = 151), we also tested a brief prospective outcome model with baseline predictor variables and functional disability at 1-month follow-up. The FA models predicting functional disability concurrently and prospectively were an excellent fit to the data. The theorized FA model for depression was a poor fit. When the model was modified to include direct pathways from the cognitive processes of pain catastrophizing and fear of pain to depressive symptoms, the model fit was significantly improved. In the examination of developmental differences between younger children and adolescent patients, duration of pain contributed to the model for younger children, whereas pain-related fears were more influential for adolescent patients.
The FA model of chronic pain appears to be applicable for pediatric patients with some modification to account for developmental differences across childhood. We discuss the developmental, theoretical, and clinical implications of these results.
本研究考察了慢性疼痛患儿的恐惧回避(FA)模型。本研究测试了多个结构方程模型,并对 8-12 岁的年幼儿童和 13-17 岁的青少年进行了两两参数比较。在 350 名儿童和青少年样本中,我们分别对功能障碍和抑郁症状进行了模型检验,预测变量为疼痛、疼痛灾难化、对疼痛的恐惧和对活动的回避,同时控制了疼痛持续时间。对于一部分患者(n=151),我们还测试了一个简短的前瞻性结果模型,该模型的基线预测变量为功能障碍,并在 1 个月的随访中进行了检验。FA 模型同时和前瞻性地预测了功能障碍,对数据的拟合度非常好。对抑郁的理论 FA 模型拟合度较差。当将模型修改为包含疼痛灾难化和对疼痛的恐惧的认知过程对抑郁症状的直接影响时,模型拟合度显著提高。在对年幼儿童和青少年患者之间的发育差异进行检查时,疼痛持续时间对年幼儿童的模型有影响,而与疼痛相关的恐惧对青少年患者的影响更大。
慢性疼痛的 FA 模型似乎适用于儿科患者,但需要进行一些修改以考虑儿童期的发育差异。我们讨论了这些结果的发展、理论和临床意义。