Centre for Molecular Nanometrology, WestCHEM, Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, UK.
Chem Soc Rev. 2012 Nov 7;41(21):7085-107. doi: 10.1039/c2cs35118h.
In recent years, Surface-Enhanced Raman Spectroscopy (SERS) has experienced a tremendous increase of attention in the scientific community, expanding to a continuously wider range of diverse applications in nanoscience, which can mostly be attributed to significant improvements in nanofabrication techniques that paved the way for the controlled design of reliable and effective SERS nanostructures. In particular, the plasmon coupling properties of interacting nanoparticles are extremely intriguing due to the concentration of enormous electromagnetic enhancements at the interparticle gaps. Recently, great efforts have been devoted to develop new nanoparticle assembly strategies in suspension with improved control over hot-spot architecture and cluster structure, laying the foundation for the full exploitation of their exceptional potential as SERS materials in a wealth of chemical and biological sensing. In this review we summarize in an exhaustive and systematic way the state-of-art of plasmonic nanoparticle assembly in suspension specifically developed for SERS applications in the last 5 years, focusing in particular on those strategies which exploited molecular linkers to engineer interparticle gaps in a controlled manner. Importantly, the novel advances in this rather new field of nanoscience are organized into a coherent overview aimed to rationally describe the different strategies and improvements in the exploitation of colloidal nanoparticle assembly for SERS application to real problems.
近年来，表面增强拉曼光谱（SERS）在科学界受到了极大的关注，其应用范围不断扩大，涉及到纳米科学的各个领域，这主要归因于纳米制造技术的显著改进，为可靠和有效的 SERS 纳米结构的可控设计铺平了道路。特别是，相互作用的纳米粒子的等离子体耦合特性由于在粒子间隙处存在巨大的电磁增强而非常有趣。最近，人们致力于开发悬浮液中的新型纳米粒子组装策略，以更好地控制热点结构和簇结构，为充分发挥其作为 SERS 材料在丰富的化学和生物传感中的特殊潜力奠定了基础。在这篇综述中，我们以详尽和系统的方式总结了过去 5 年来专门为 SERS 应用而开发的悬浮液中等离子体纳米粒子组装的最新进展，特别关注那些利用分子连接物以可控方式构建粒子间间隙的策略。重要的是，将这一新兴纳米科学领域的新进展组织成一个连贯的概述，旨在合理描述胶体纳米粒子组装在 SERS 应用于实际问题方面的不同策略和改进。
