牙科组织工程与再生中的干细胞及生物材料研究
Stem cell and biomaterials research in dental tissue engineering and regeneration.
作者信息
Horst Orapin V, Chavez Miquella G, Jheon Andrew H, Desai Tejal, Klein Ophir D
机构信息
Division of Endodontics, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, USA.
出版信息
Dent Clin North Am. 2012 Jul;56(3):495-520. doi: 10.1016/j.cden.2012.05.009.
Abstract
This review summarizes approaches used in tissue engineering and regenerative medicine, with a focus on dental applications. Dental caries and periodontal disease are the most common diseases resulting in tissue loss. To replace or regenerate new tissues, various sources of stem cells have been identified such as somatic stem cells from teeth and peridontium. Advances in biomaterial sciences including microfabrication, self-assembled biomimetic peptides, and 3-dimensional printing hold great promise for whole-organ or partial tissue regeneration to replace teeth and periodontium.
摘要
本综述总结了组织工程和再生医学中使用的方法，重点是牙科应用。龋齿和牙周病是导致组织丧失的最常见疾病。为了替换或再生新组织，已确定了各种干细胞来源，如来自牙齿和牙周组织的体干细胞。生物材料科学的进展，包括微制造、自组装仿生肽和三维打印，对于全器官或部分组织再生以替换牙齿和牙周组织具有巨大潜力。
相似文献
1
Stem cell and biomaterials research in dental tissue engineering and regeneration.
Dent Clin North Am. 2012 Jul;56(3):495-520. doi: 10.1016/j.cden.2012.05.009.
2
Tailored Biomaterials for Therapeutic Strategies Applied in Periodontal Tissue Engineering.
Stem Cells Dev. 2019 Aug 1;28(15):963-973. doi: 10.1089/scd.2019.0016. Epub 2019 May 24.
3
Stem cell-delivery therapeutics for periodontal tissue regeneration.
Biomaterials. 2012 Sep;33(27):6320-44. doi: 10.1016/j.biomaterials.2012.05.048. Epub 2012 Jun 12.
4
Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium.
Stem Cells Dev. 2019 Aug 1;28(15):974-985. doi: 10.1089/scd.2019.0031.
5
Concise Review: Periodontal Tissue Regeneration Using Stem Cells: Strategies and Translational Considerations.
Stem Cells Transl Med. 2019 Apr;8(4):392-403. doi: 10.1002/sctm.18-0181. Epub 2018 Dec 26.
6
Constructs and scaffolds employed to regenerate dental tissue.
Dent Clin North Am. 2012 Jul;56(3):577-88. doi: 10.1016/j.cden.2012.05.008.
7
Periodontal ligament stem cells: an update and perspectives.
J Investig Clin Dent. 2014 May;5(2):81-90. doi: 10.1111/jicd.12089. Epub 2014 Mar 7.
8
Biomaterials for Periodontal Regeneration.
Dent Clin North Am. 2022 Oct;66(4):659-672. doi: 10.1016/j.cden.2022.05.011. Epub 2022 Sep 11.
9
Stem cells, tissue engineering and periodontal regeneration.
Aust Dent J. 2014 Jun;59 Suppl 1:117-30. doi: 10.1111/adj.12100. Epub 2013 Sep 23.
10
Promise of periodontal ligament stem cells in regeneration of periodontium.
Stem Cell Res Ther. 2011 Jul 28;2(4):33. doi: 10.1186/scrt74.
引用本文的文献
1
Tomographic evaluation of apexogenesis with human treated dentin matrix in young permanent molars: a split-mouth randomized controlled clinical trial.
BMC Oral Health. 2025 May 7;25(1):692. doi: 10.1186/s12903-025-05997-1.
2
Histological evaluation of the regenerative potential of a novel photocrosslinkable gelatin-treated dentin matrix hydrogel in direct pulp capping: an animal study.
BMC Oral Health. 2024 Jan 19;24(1):114. doi: 10.1186/s12903-024-03868-9.
3
Biopolymers and Their Application in Bioprinting Processes for Dental Tissue Engineering.
Pharmaceutics. 2023 Aug 10;15(8):2118. doi: 10.3390/pharmaceutics15082118.
4
A Systematic Review on Polyester Scaffolds in Dental Three-dimensional Cell Printing: Transferring Art from the Laboratories to the Clinics.
Int J Clin Pediatr Dent. 2023 May-Jun;16(3):494-498. doi: 10.5005/jp-journals-10005-2609.
5
Biodegradation of an injectable treated dentin matrix hydrogel as a novel pulp capping agent for dentin regeneration.
BMC Oral Health. 2023 Feb 25;23(1):126. doi: 10.1186/s12903-023-02831-4.
6
Tissue Engineering with Stem Cell from Human Exfoliated Deciduous Teeth (SHED) and Collagen Matrix, Regulated by Growth Factor in Regenerating the Dental Pulp.
Polymers (Basel). 2022 Sep 6;14(18):3712. doi: 10.3390/polym14183712.
7
Application of Selected Biomaterials and Stem Cells in the Regeneration of Hard Dental Tissue in Paediatric Dentistry-Based on the Current Literature.
Nanomaterials (Basel). 2021 Dec 13;11(12):3374. doi: 10.3390/nano11123374.
8
Hard Dental Tissues Regeneration-Approaches and Challenges.
Materials (Basel). 2021 May 14;14(10):2558. doi: 10.3390/ma14102558.
9
Influence of Materials Properties on Bio-Physical Features and Effectiveness of 3D-Scaffolds for Periodontal Regeneration.
Molecules. 2021 Mar 15;26(6):1643. doi: 10.3390/molecules26061643.
10
Geometrical Structure of Honeycomb TCP to Control Dental Pulp-Derived Cell Differentiation.
Materials (Basel). 2020 Nov 16;13(22):5155. doi: 10.3390/ma13225155.
本文引用的文献
1
A functional agarose-hydroxyapatite scaffold for osteochondral interface regeneration.
Biomaterials. 2012 Jul;33(21):5247-58. doi: 10.1016/j.biomaterials.2012.03.076. Epub 2012 Apr 22.
2
Revascularization and tissue regeneration of an empty root canal space is enhanced by a direct blood supply and stem cells.
Dent Traumatol. 2013 Apr;29(2):84-91. doi: 10.1111/j.1600-9657.2012.01136.x. Epub 2012 Apr 23.
3
Generation of human β-thalassemia induced pluripotent stem cells from amniotic fluid cells using a single excisable lentiviral stem cell cassette.
J Reprod Dev. 2012;58(4):404-9. doi: 10.1262/jrd.2011-046. Epub 2012 Apr 13.
4
Efficient commitment to functional CD34+ progenitor cells from human bone marrow mesenchymal stem-cell-derived induced pluripotent stem cells.
PLoS One. 2012;7(4):e34321. doi: 10.1371/journal.pone.0034321. Epub 2012 Apr 9.
5
Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain.
Stem Cells. 2012 Jun;30(6):1120-33. doi: 10.1002/stem.1104.
6
Endothelial cell co-culture mediates maturation of human embryonic stem cell to pancreatic insulin producing cells in a directed differentiation approach.
J Vis Exp. 2012 Mar 27(61):3759. doi: 10.3791/3759.
7
Chitosan-based scaffolds for the support of smooth muscle constructs in intestinal tissue engineering.
Biomaterials. 2012 Jun;33(19):4810-7. doi: 10.1016/j.biomaterials.2012.03.051. Epub 2012 Apr 5.
8
Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs.
Cell Stem Cell. 2012 Apr 6;10(4):385-97. doi: 10.1016/j.stem.2012.01.018.
9
Injectable hydrogels for central nervous system therapy.
Biomed Mater. 2012 Apr;7(2):024101. doi: 10.1088/1748-6041/7/2/024101. Epub 2012 Mar 29.
10
Engineering functional bladder tissues.
J Tissue Eng Regen Med. 2013 Jul;7(7):515-22. doi: 10.1002/term.547. Epub 2012 Mar 21.
Zotero 插件