牙科组织工程与再生中的干细胞及生物材料研究
Stem cell and biomaterials research in dental tissue engineering and regeneration.
作者信息
Horst Orapin V, Chavez Miquella G, Jheon Andrew H, Desai Tejal, Klein Ophir D
机构信息
Division of Endodontics, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, USA.
出版信息
Dent Clin North Am. 2012 Jul;56(3):495-520. doi: 10.1016/j.cden.2012.05.009.
Abstract
This review summarizes approaches used in tissue engineering and regenerative medicine, with a focus on dental applications. Dental caries and periodontal disease are the most common diseases resulting in tissue loss. To replace or regenerate new tissues, various sources of stem cells have been identified such as somatic stem cells from teeth and peridontium. Advances in biomaterial sciences including microfabrication, self-assembled biomimetic peptides, and 3-dimensional printing hold great promise for whole-organ or partial tissue regeneration to replace teeth and periodontium.
摘要
本综述总结了组织工程和再生医学中使用的方法，重点是牙科应用。龋齿和牙周病是导致组织丧失的最常见疾病。为了替换或再生新组织，已确定了各种干细胞来源，如来自牙齿和牙周组织的体干细胞。生物材料科学的进展，包括微制造、自组装仿生肽和三维打印，对于全器官或部分组织再生以替换牙齿和牙周组织具有巨大潜力。
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