Goodis Harold E, Kinaia Bassam Michael, Kinaia Atheel M, Chogle Sami M A
The Boston University Institute for Dental Research and Education, PO Box 505097, Dubai Healthcare City, Dubai, United Arab Emirates.
Dent Clin North Am. 2012 Jul;56(3):677-89. doi: 10.1016/j.cden.2012.05.007. Epub 2012 Jun 23.
The work performed by researchers in regenerative endodontics and tissue engineering over the last decades has been superb; however, many questions remain to be answered. The basic biologic mechanisms must be elucidated that will allow the development of dental pulp and dentin in situ. Stress must be placed on the many questions that will lead to the design of effective, safe treatment options and therapies. This article discusses those questions, the answers to which may become the future of regenerative endodontics. The future remains bright, but proper support and patience are required.
在过去几十年里，再生牙髓病学和组织工程领域的研究人员所做的工作堪称卓越；然而，仍有许多问题有待解答。必须阐明基本的生物学机制，以便实现牙髓和牙本质的原位发育。必须重视那些将有助于设计有效、安全的治疗方案和疗法的诸多问题。本文讨论了这些问题，其答案可能会成为再生牙髓病学的未来。前景依然光明，但需要适当的支持和耐心。
