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0.5%左旋布比卡因或0.5%布比卡因与2%利多卡因混合用于浅表锥体外阻滞的比较。

Comparison of levobupivacaine 0.5% or bupivacaine 0.5% both in a mixture with lidocaine 2% for superficial extraconal blockade.

作者信息

Ahmad Nauman, Zahoor Abdul, Al Assiri Abdullah, Al Jastaneiah Sabah, Riad Waleed

机构信息

Department of Anesthesia, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

出版信息

Middle East Afr J Ophthalmol. 2012 Jul-Sep;19(3):330-3. doi: 10.4103/0974-9233.97945.

Abstract

PURPOSE

To evaluate the quality and efficacy of Peribulbar blockade for superficial extraconal anesthesia with levobupivacaine 0.5% versus bupivacaine 0.5%, both combined with lidocaine 2% for patients undergoing phacoemulsification.

MATERIALS AND METHODS

In this prospective, double blind study, 150 patients were randomly divided into two groups: group-1 received a Peribulbar block (PB) with a mixture of evobupivacaine 0.5% and lidocaine 2% while group-2 received a PB with a mixture of bupivacaine 0.5% and lidocaine 2%. The block was performed by insertion of a short needle (15 mm) in infra-temporal space just above inferior orbital notch. An initial volume of 6 9 ml of either mixture was injected until total upper eyelid drop. Akinesia score was assessed at 2, 5, and 10 min after the block. The degree of pain was assessed by a verbal rating scale immediately after block, at the end of surgery and 4 h postoperatively. The patients and surgeons were asked to rate their satisfaction level of the quality of block postoperatively. Data were analyzed with the unpaired, two-tailed t-test and the Chi-square test as appropriate. P < 0.05 was considered statistically significant.

RESULTS

There were no significant differences between groups with respect to the akinesia score (P = 0.2) at 2, 5, and 10 min, the number of supplementary injections (P = 0.84) and initial and total required volume of local anesthetics (P = 0.80 and 0.81, respectively). There was no significant difference between the groups regarding surgeon and patient satisfaction (P = 0.53 and P = 0.74, respectively). Similarly the verbal rating scales assessed at three different occasions were not significantly different between the groups (P > 0.05 all cases). The need for additional intra-operative topical anesthetic was also similar between the groups. (P = 0.69).

CONCLUSIONS

Superficial extra-conal block with a mixture of levobupivicaine 0.5% and lidocaine 2% or bupivicaine 0.5% and lidocaine 2% provides similar block quality and efficacy.

摘要

目的

评估0.5%左旋布比卡因与0.5%布比卡因联合2%利多卡因用于球周阻滞行超声乳化白内障吸除术患者的表面锥体外麻醉的质量和效果。

材料与方法

在这项前瞻性双盲研究中,150例患者被随机分为两组:第一组接受0.5%依替卡因与2%利多卡因混合液的球周阻滞(PB),而第二组接受0.5%布比卡因与2%利多卡因混合液的PB。通过在眶下切迹上方的颞下间隙插入短针(15 mm)进行阻滞。注入6~9 ml的任一混合液初始量,直至上睑完全下垂。在阻滞后2、5和10分钟评估运动不能评分。在阻滞后即刻、手术结束时和术后4小时通过语言评分量表评估疼痛程度。要求患者和外科医生对术后阻滞质量的满意度进行评分。数据采用不成对双尾t检验和卡方检验进行适当分析。P<0.05被认为具有统计学意义。

结果

两组在2、5和10分钟时的运动不能评分(P = 0.2)、追加注射次数(P = 0.84)以及局部麻醉药的初始和总需求量(分别为P = 0.80和0.81)方面无显著差异。两组在外科医生和患者满意度方面无显著差异(分别为P = 0.53和P = 0.74)。同样,在三个不同时间点评估的语言评分量表在两组之间也无显著差异(所有病例P>0.05)。两组术中额外使用表面麻醉剂的需求也相似(P = 0.69)。

结论

0.5%左旋布比卡因与2%利多卡因或0.5%布比卡因与2%利多卡因混合液的表面锥体外阻滞提供相似的阻滞质量和效果。

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