Department of Pediatric Nephrology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, Route 804, 6500 HB, Nijmegen, The Netherlands.
Eur J Pediatr. 2013 Mar;172(3):413-6. doi: 10.1007/s00431-012-1800-y. Epub 2012 Jul 31.
Mid-aortic syndrome is characterized by narrowing of the abdominal aorta, usually with the involvement of renal arteries and other visceral branches. The combination of the presence of an abdominal bruit, diminished or absent pulsations of the lower extremities, and a blood pressure discrepancy between upper and lower extremities is the classic triad associated with mid-aortic syndrome. However, it has a wide variety of clinical symptoms, and awareness of the variable presentation can lead to early diagnosis of the vascular anomaly. We report three cases presenting at three different stages of this disease, such as hydrops fetalis, refractory hypertension, and intracerebral bleeding. In conclusion, these cases highlight the importance of blood pressure measurements in all patients and accurate physical examination for early recognition of a mid-aortic syndrome.
主动脉中段综合征的特征为腹主动脉狭窄,通常伴有肾动脉和其他内脏分支受累。存在腹部杂音、下肢搏动减弱或消失以及上下肢血压差异的三联征与主动脉中段综合征相关。然而,其临床表现多种多样,对各种表现的认识有助于早期诊断血管异常。我们报告了三例处于该病不同阶段的病例,包括胎儿水肿、难治性高血压和颅内出血。总之,这些病例强调了对所有患者进行血压测量和准确体格检查以早期识别主动脉中段综合征的重要性。