Løvset T
Acta Obstet Gynecol Scand. 1990;69(6):521-6. doi: 10.3109/00016349009013330.
The experience of 1254 women who had Multiload 250s (MLCu250) and 754 women who had Multiload 375s (MLCu375) inserted by the author was evaluated. The performance of the two Multiload models was similar over 4 years of use, except for a significantly lower (p less than 0.05) pregnancy rate for the MLCu375 (4-year cumulative life table rates: 3.0 vs 5.4 per 100 women). Use of the MLCu250 and MLCu375 provided women with a very safe method of contraception. Many of the removals for medical reasons other than bleeding, pain or pelvic inflammatory disease (PID) appeared to be unrelated to IUD use. Thirty-nine women had their IUDs removed for suspected PID, but the diagnosis of PID was confirmed in only 44% of these cases. The overall rate of confirmed cases of PID was 0.3 per 100 woman-years. Except for a higher rate of PID during the first few months of Multiload use, the results of the study did not indicate that IUD use is associated with an increased risk of PID. Multiload use did not impair future pregnancy or affect the outcomes of these pregnancies.
对作者为1254名妇女植入多负载250型（MLCu250）宫内节育器以及为754名妇女植入多负载375型（MLCu375）宫内节育器的经验进行了评估。在4年的使用期内，两种多负载型号的性能相似，但MLCu375的妊娠率显著更低（p<0.05）（4年累积生命表率：每100名妇女中分别为3.0例和5.4例）。使用MLCu250和MLCu375为妇女提供了一种非常安全的避孕方法。许多因出血、疼痛或盆腔炎（PID）以外的医疗原因取出宫内节育器的情况似乎与宫内节育器的使用无关。39名妇女因疑似PID取出了宫内节育器，但其中只有44%的病例确诊为PID。确诊PID的总体发生率为每100妇女年0.3例。除了在使用多负载宫内节育器的最初几个月PID发生率较高外，研究结果并未表明使用宫内节育器会增加PID风险。使用多负载宫内节育器不会损害未来的妊娠，也不会影响这些妊娠的结局。
