Fang X C, Xiang B R, An D K
Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing.
Yao Xue Xue Bao. 1990;25(6):462-8.
Thirty-eight samples of Moutan (Paeonia suffruticosa Andr.) Cortex obtained from three different regions (Southwest, East and Middle China) and two samples of unknown region were subjected to analysis with pyrolysis-high resolution gas chromatography (Py-HRGC). Each sample was thus characterized by the peak area of 41 peaks in each Py-HRGC profile. Discriminant analysis (DA), PRIMA and SIMCA pattern recognition were used to recognize the 40 x 41 data matrix. These data analysis gave satisfactory results (DA, 100% correct; PRIMA, 100% correct, 92.2% unique; SIMCA, 92.2% correct, 79% unique). The correct classification of Moutan Cortex for the unknown territory was obtained by three pattern recognition methods. The results showed that Py-HRGC/pattern recognition technique might be a potential tool for the identification of Chinese traditional medicine.
从三个不同地区(中国西南部、东部和中部)采集的38份牡丹皮样本以及两份来源不明地区的样本,采用热解-高分辨率气相色谱法(Py-HRGC)进行分析。每个样本通过各自Py-HRGC图谱中41个峰的峰面积进行表征。使用判别分析(DA)、PRIMA和SIMCA模式识别方法对40×41数据矩阵进行识别。这些数据分析得出了令人满意的结果(DA,正确率100%;PRIMA,正确率100%,独特性92.2%;SIMCA,正确率92.2%,独特性79%)。通过三种模式识别方法实现了对来源不明地区牡丹皮的正确分类。结果表明,Py-HRGC/模式识别技术可能是鉴定中药的一种潜在工具。