Araujo Marcos Miranda, Massuda Eduardo Tanaka, Hyppolito Miguel Angelo
Department of Oftalmology, Otorrhinolaryngology and Head Neck Surgery, Faculty of Medicine of Ribeirao Preto, USP, São Paulo, SP, Brazil.
Acta Cir Bras. 2012 Aug;27(8):566-71. doi: 10.1590/s0102-86502012000800009.
To compare the role of transitory latex and sylastic® implants in tympanoplasty on the closure of tympanic perforations.
A randomized double-blind prospective study was conducted on 107 patients with chronic otitis media submitted to underlay tympanoplasty and divided at random into three groups: control with no transitory implant, latex membrane group, and sylastic® membrane group.
Greater graft vascularization occurred in the latex membrane group (p<0.05). Good biocompatibility was obtained with the use of the latex and silicone implants, with no effect on the occurrence of infection, otorrhea or otorragy.
The use of a transitory latex implant induced greater graft vascularization, with a biocompatible interaction with the tissue of the human tympanic membrane.
比较暂时性乳胶和硅橡胶植入物在鼓室成形术中对鼓膜穿孔闭合的作用。
对107例接受内植法鼓室成形术的慢性中耳炎患者进行了一项随机双盲前瞻性研究，随机分为三组：无暂时性植入物对照组、乳胶膜组和硅橡胶膜组。
乳胶膜组移植物血管化程度更高（p<0.05）。使用乳胶和硅橡胶植入物具有良好的生物相容性，对感染、耳漏或耳出血的发生没有影响。
使用暂时性乳胶植入物可诱导更高程度的移植物血管化，与人类鼓膜组织具有生物相容性相互作用。
